RXFP3

Relaksinu/insulinu-slična familija, peptidni receptor 4
Identifikatori
Simboli	RXFP3; GPCR135; MGC141998; MGC142000; RLN3R1; SALPR
Vanjski ID	OMIM: 609445 MGI: 2441827 HomoloGene: 9568 IUPHAR: RXFP3 GeneCards: RXFP3 Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu-sličnog receptora • receptorska aktivnost • aktivnost N-formil peptidnog receptora
Celularna komponenta	• integralno sa ćelijskom membranom • membrana
Biološki proces	• prenos signala • signalni put G-protein spregnutog receptora • elevacija koncentracije citosolnih jona kalcijuma tokom G-proteinske signalizacije)
Pregled RNK izražavanja
	podaci
Ortolozi

edit

RXFP3, relaksinu/insulinu-slična familija, peptidni receptor 3, je humani G-protein spregnuti receptor.^[1]

Povezano

Relaksinski receptor

Referfence

↑ „Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3”.

Literatura

Bathgate RA, Ivell R, Sanborn BM, et al. (2005). „Receptors for relaxin family peptides.”. Ann. N. Y. Acad. Sci. 1041: 61–76. DOI:10.1196/annals.1282.010. PMID 15956688.
Bathgate RA, Ivell R, Sanborn BM, et al. (2006). „International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.”. Pharmacol. Rev. 58 (1): 7–31. DOI:10.1124/pr.58.1.9. PMID 16507880.
Matsumoto M, Kamohara M, Sugimoto T, et al. (2000). „The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors.”. Gene 248 (1-2): 183–9. DOI:10.1016/S0378-1119(00)00123-2. PMID 10806363.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Liu C, Eriste E, Sutton S, et al. (2004). „Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.”. J. Biol. Chem. 278 (50): 50754–64. DOI:10.1074/jbc.M308995200. PMID 14522968.
Liu C, Chen J, Kuei C, et al. (2005). „Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.”. Mol. Pharmacol. 67 (1): 231–40. DOI:10.1124/mol.104.006700. PMID 15465925.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ (2005). „Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry.”. Ann. N. Y. Acad. Sci. 1041: 332–7. DOI:10.1196/annals.1282.053. PMID 15956730.

Vanjske veze

„Relaxin Family Peptide Receptors: RXFP3”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.

[entrez-1] „Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3”.

[1]

RXFP3

Povezano

Referfence

Literatura

Vanjske veze

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