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G protein spregnuti receptor 126
Identifikatori
Simboli	GPR126; APG1; DREG; PS1TP2; VIGR
Vanjski ID	OMIM: 612243 MGI: 1916151 HomoloGene: 10724 IUPHAR: GPR126 GeneCards: GPR126 Gene
Ontologija gena
Molekularna funkcija	• aktivnost G protein spregnutog receptora;
Celularna komponenta	• integralno sa ćelijskom membranom; • integralno sa membranom;
Biološki proces	• signalni put G protein spregnutog receptora; • neuropeptidni signalni put;
Pregled RNK izražavanja
	podaci
Ortolozi

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G protein spregnuti receptor 126 je protein koji je kod ljudi kodiran GPR126 genom.^[1]^[2] On učestvuje u procesu mijelinacija.^[3]

Reference

↑ Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (Feb 2003). „There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini”. Biochem Biophys Res Commun 301 (3): 725–34. DOI:10.1016/S0006-291X(03)00026-3. PMID 12565841.
↑ „Entrez Gene: GPR126 G protein-coupled receptor 126”.
↑ Monk KR, Oshima K, Jörs S, Heller S, Talbot WS (May 2011). „Gpr126 is essential for peripheral nerve development and myelination in mammals”. Development 138 (13): 2673–2680. DOI:10.1242/dev.062224. PMC 3109596. PMID 21613327. Lay summary – news.wustl.edu.

Literatura

Matoba R, Okubo K, Hori N, et al. (1994). „The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression”. Gene 146 (2): 199–207. DOI:10.1016/0378-1119(94)90293-3. PMID 8076819.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40–5. DOI:10.1038/ng1285. PMID 14702039.
Kristiansen TZ, Bunkenborg J, Gronborg M, et al. (2005). „A proteomic analysis of human bile”. Mol. Cell Proteomics 3 (7): 715–28. DOI:10.1074/mcp.M400015-MCP200. PMID 15084671.
Moriguchi T, Haraguchi K, Ueda N, et al. (2005). „DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites”. Genes Cells 9 (6): 549–60. DOI:10.1111/j.1356-9597.2004.00743.x. PMID 15189448.
Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). „The human and mouse repertoire of the adhesion family of G-protein-coupled receptors”. Genomics 84 (1): 23–33. DOI:10.1016/j.ygeno.2003.12.004. PMID 15203201.
Stehlik C, Kroismayr R, Dorfleutner A, et al. (2004). „VIGR--a novel inducible adhesion family G-protein coupled receptor in endothelial cells”. FEBS Lett. 569 (1–3): 149–55. DOI:10.1016/j.febslet.2004.05.038. PMID 15225624.
Otsuki T, Ota T, Nishikawa T, et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries”. DNA Res. 12 (2): 117–26. DOI:10.1093/dnares/12.2.117. PMID 16303743.
Liu T, Qian WJ, Gritsenko MA, et al. (2006). „Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry”. J. Proteome Res. 4 (6): 2070–80. DOI:10.1021/pr0502065. PMC 1850943. PMID 16335952.

[pmid12565841-1] Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB (Feb 2003). „There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini”. Biochem Biophys Res Commun 301 (3): 725–34. DOI:10.1016/S0006-291X(03)00026-3. PMID 12565841.

[entrez-2] „Entrez Gene: GPR126 G protein-coupled receptor 126”.

[pmid21613327-3] Monk KR, Oshima K, Jörs S, Heller S, Talbot WS (May 2011). „Gpr126 is essential for peripheral nerve development and myelination in mammals”. Development 138 (13): 2673–2680. DOI:10.1242/dev.062224. PMC 3109596. PMID 21613327. Lay summary – news.wustl.edu.

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