Članovi familije 'uvojitih' proteina su 7-transmembranski receptori za Wnt signalne proteine. Izražavanje FZD2 gena je razvojno regulisano, sa visokim nivoima izraženim u bubrezima i plučima fetusa, i u crevima i jajnicima odraslih osoba.[3]
Reference
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↑Sagara N, Toda G, Hirai M, Terada M, Katoh M (Dec 1998). „Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7”. Biochem Biophys Res Commun252 (1): 117–22. DOI:10.1006/bbrc.1998.9607. PMID9813155.
Wang Y, Macke JP, Abella BS, et al. (1996). „A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.”. J. Biol. Chem.271 (8): 4468–76. DOI:10.1074/jbc.271.8.4468. PMID8626800.
Hering H, Sheng M (2002). „Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95.”. FEBS Lett.521 (1–3): 185–9. DOI:10.1016/S0014-5793(02)02831-4. PMID12067714.
Oishi I, Suzuki H, Onishi N, et al. (2004). „The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway”. Genes Cells8 (7): 645–54. DOI:10.1046/j.1365-2443.2003.00662.x. PMID12839624.
Omoto S, Hayashi T, Kitahara K, et al. (2004). „Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R)”. Ophthalmic Genet.25 (2): 81–90. DOI:10.1080/13816810490514270. PMID15370539.
„Frizzled Receptors: FZD2”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.
