Somatostatin deluje na mnogim lokacijama i inhibira oslobađanje hormona i drugih sekretornih proteina. Biološki efekti somatostatina su posredovani familijom G protein-spregnutih receptora čije izražavanje je specifično za pojedina tkiva. SSTR4 u znatnoj meri izražen u jejunumu i želucu.[2]
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Zatelli MC, Tagliati F, Taylor JE, et al. (2001). „Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line tt.”. J. Clin. Endocrinol. Metab.86 (5): 2161–9. DOI:10.1210/jc.86.5.2161. PMID11344221.
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Papotti M, Bongiovanni M, Volante M, et al. (2002). „Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis.”. Virchows Arch.440 (5): 461–75. DOI:10.1007/s00428-002-0609-x. PMID12021920.
Zatelli MC, Tagliati F, Piccin D, et al. (2002). „Somatostatin receptor subtype 1-selective activation reduces cell growth and calcitonin secretion in a human medullary thyroid carcinoma cell line.”. Biochem. Biophys. Res. Commun.297 (4): 828–34. DOI:10.1016/S0006-291X(02)02307-0. PMID12359227.
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Vanjske veze
„Somatostatin Receptors: sst1”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.
