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Purinski receptor P2Y, G-protein spregnuti, 14
Identifikatori
Simboli	P2RY14; GPR105; KIAA0001; P2Y14
Vanjski ID	OMIM: 610116 MGI: 2155705 HomoloGene: 15769 IUPHAR: P2Y14 GeneCards: P2RY14 Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu-sličnog receptora; • receptorska aktivnost; • aktivnost purinskog nukleotidnog receptora, G-protein spregnutog; • aktivnost UDP-aktiviranog nukleotidnog receptora;
Celularna komponenta	• membrana; • integralno sa membranom;
Biološki proces	• prenos signala; • signalni put G-protein spregnutog receptora;
Pregled RNK izražavanja
	podaci
Ortolozi

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P2Y purinoceptor 14 je protein koji je kod ljudi kodiran P2RY14 genom.^[1]

Proizvod P2RY14 gena pripada familiji G-protein spregnutih receptora. Postoji nekoliko tipova receptora sa različitom farmakološkom selektivnošću za razne adenozinske i uridinske nukleotide. Ovaj receptor je P2Y purinski receptor za UDP-glukozu i druge UDP-šećere spregnute sa G-proteinima. Smatra se da on učestvuje u dejstvu imunskog sistema putem regulacije matičnih ćelija, kao i u neuroimunskim funkcijama. Dve transkriptne varijante koje kodiraju isti protein su poznate.^[1]

Povezano

P2Y receptor

Reference

↑ ^1,0 ^1,1 „Entrez Gene: P2RY14 purinergic receptor P2Y, G-protein coupled, 14”.

Literatura

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Lee BC, Cheng T, Adams GB, et al. (2003). „P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrow hematopoietic stem cells.”. Genes Dev. 17 (13): 1592–604. DOI:10.1101/gad.1071503. PMC 196132. PMID 12842911.
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Spoljašnje veze

„P2Y Receptors: P2Y₁₄”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.