P2RY13

Purinski receptor P2Y, G-protein spregnuti, 13
Identifikatori
Simboli	P2RY13; GPCR1; FKSG77; GPR86; GPR94; P2Y13; SP174
Vanjski ID	OMIM: 606380 MGI: 1921441 HomoloGene: 12543 IUPHAR: P2Y13 GeneCards: P2RY13 Gene
Ontologija gena
Ontologija gena
Pregled RNK izražavanja
	podaci
Ortolozi

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P2Y purinoceptor 13 je protein koji je kod ljudi kodiran P2RY13 genom.^[1]^[2]^[3]

Proizvod ovog gena, P2Y₁₃, je član familije G-protein spregnutih receptora. Ova familija ima nekoliko tipova receptora sa različitom farmakološkom selektivnosti za razne adenozinske i uridinske nukleotide. Oni se preklapaju u nekim slučajevima. Endogeni ligand ovog receptora je ADP. Dve transkriptne varijante koje kodiraju isti protein su poznate.^[3]

Povezano

P2Y receptor

Reference

↑ Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). „An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors”. J Mol Biol 307 (3): 799–813. DOI:10.1006/jmbi.2001.4520. PMID 11273702.
↑ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). „Discovery and mapping of ten novel G protein-coupled receptor genes”. Gene 275 (1): 83–91. DOI:10.1016/S0378-1119(01)00651-5. PMID 11574155.
↑ ^3,0 ^3,1 „Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13”.

Literatura

Communi D, Gonzalez NS, Detheux M, et al. (2001). „Identification of a novel human ADP receptor coupled to G(i).”. J. Biol. Chem. 276 (44): 41479–85. DOI:10.1074/jbc.M105912200. PMID 11546776.
Zhang FL, Luo L, Gustafson E, et al. (2002). „P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse.”. J. Pharmacol. Exp. Ther. 301 (2): 705–13. DOI:10.1124/jpet.301.2.705. PMID 11961076.
Takeda S, Kadowaki S, Haga T, et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1–3): 97–101. DOI:10.1016/S0014-5793(02)02775-8. PMID 12044878.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

Vanjske veze

„P2Y Receptors: P2Y₁₃”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.

[pmid11273702-1] Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). „An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors”. J Mol Biol 307 (3): 799–813. DOI:10.1006/jmbi.2001.4520. PMID 11273702.

[pmid11574155-2] Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). „Discovery and mapping of ten novel G protein-coupled receptor genes”. Gene 275 (1): 83–91. DOI:10.1016/S0378-1119(01)00651-5. PMID 11574155.

[entrez-3] 3,0 ^3,1 „Entrez Gene: P2RY13 purinergic receptor P2Y, G-protein coupled, 13”.

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P2RY13

Povezano

Reference

Literatura

Vanjske veze

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