GPR135

G protein-spregnuti receptor 135

Identifikatori

GPR135; HUMNPIIY20

Vanjski ID

OMIM: 607970 MGI: 2676315 HomoloGene: 11211 IUPHAR: GPR135 GeneCards: GPR135 Gene

Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu sličnog receptora • receptorska aktivnost • masno kiselinsko vezivanje
Celularna komponenta	• integralno sa ćelijskom membranom • membrana • vezikule endocitoze
Biološki proces	• prenos signal • signalni put G-protein spregnutog receptora • hormonska sekrecija

Pregled RNK izražavanja

podaci

Ortolozi

Vrsta

Čovek

Miš

RefSeq (mRNA)

RefSeq (protein)

Lokacija (UCSC)

Chr 12:
72.99 - 72.99 Mb

PubMed pretraga

[1]

[2]

GPR135, G protein-spregnuti receptor 135, je protein koji je kod čoveka kodiran GPR135 genom.^[1]^[2]

Literatura

↑ Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB (Nov 2003). „Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives”. FEBS Lett 554 (3): 381–8. DOI:10.1016/S0014-5793(03)01196-7. PMID 14623098.
↑ „Entrez Gene: GPR135 G protein-coupled receptor 135”.

Dodatna literatura

Kunz D, Gerard NP, Gerard C (1992). „The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog.”. J. Biol. Chem. 267 (13): 9101–6. PMID 1374385.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Vassilatis DK, Hohmann JG, Zeng H, et al. (2003). „The G protein-coupled receptor repertoires of human and mouse.”. Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903–8. DOI:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
Vanti WB, Nguyen T, Cheng R, et al. (2003). „Novel human G-protein-coupled receptors.”. Biochem. Biophys. Res. Commun. 305 (1): 67–71. DOI:10.1016/S0006-291X(03)00709-5. PMID 12732197.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.

Transmembranski receptor: G protein spregnuti receptori

Klasa A: Rodopsinu slični

Neurotransmiter

Adrenergički	α1 (A, B, D) • α2 (A, B, C) • β1 • β2 • β3
Purinski	Adenozinski (A1, A2A, A2B, A3) • P2Y (1, 2, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14)
Serotoninski	(svi osim 5-HT3) 5-HT1 (A, B, D, E, F) • 5-HT2 (A, B, C) • 5-HT (4, 5A, 6, 7)
Drugi	Acetilholin (M1, M2, M3, M4, M5) • Dopamin (D1, D2, D3, D4, D5) • Histamin (H1, H2, H3, H4) • Melatonin (1A, 1B, 1C) • TAAR (1, 2, 3, 5, 6, 8, 9)

Metaboliti i
signalni molekuli

Eikozanoidni	CysLT (1, 2) • LTB4 (1, 2) • FPRL1 • OXE • Prostaglandin (DP (1, 2), EP (1, 2, 3, 4), FP) • Prostaciklin • Tromboksan
Drugi	Žučna kiselina • Kanabinoidni (CB1, CB2, GPR (18, 55, 119)) • EBI2 • Estrogen • Slobodna masna kiselina (1, 2, 3, 4) • Laktat • Lizofosfatidna kiselina (1, 2, 3, 4, 5, 6) • Lizofosfolipid (1, 2, 3, 4, 5, 6, 7, 8) • Niacin (1, 2) • Oksoglutarat • PAF • Sfingozin-1-fosfat (1, 2, 3, 4, 5) • Sukcinat

Peptid

Neuropeptidni

B/W (1, 2) • FF (1, 2) • S • Y (1, 2, 4, 5) • Neuromedin (B, U (1, 2)) • Neurotenzin (1, 2)

Drugi

Anafilatoksin (C3a, C5a) • Angiotenzin (1, 2) • Apelin • Bombezin (BRS3, GRPR, NMBR) • Bradikinin (B1, B2) • Hemokin • Holecistokinin (A, B) • Endotelin (A, B) • Formil peptid (1, 2, 3) • FSH • Galanin (1, 2, 3) • GHB receptor • Gonadotropin-oslobađajući hormon (1, 2) • Grelin • Kispeptin • Luteinizirajući hormon/horiogonadotropin • MAS (1, 1L, D, E, F, G, X1, X2, X3, X4) • Melanokortin (1, 2, 3, 4, 5) • MCHR (1, 2) • Motilin • Opioidni (δ, κ, μ, Nociceptin & ζ, ali ne σ) • Oreksin (1, 2) • Oksitocin • Prokineticin (1, 2) • Prolaktin-oslobađajući peptid • Relaksin (1, 2, 3, 4) • Somatostatin (1, 2, 3, 4, 5) • Tahikinin (1, 2, 3) • Tirotropin • Tirotropin-oslobađajući hormon • Urotenzin-II • Vazopresin (1A, 1B, 2)

Razno

Orfan	GPR (1, 3, 4, 6, 12, 15, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 31, 32, 33, 34, 35, 37, 39, 42, 44, 45, 50, 52, 55, 61, 62, 63, 65, 68, 75, 77, 78, 81, 82, 83, 84, 85, 87, 88, 92, 101, 103, 109A, 109B, 119, 120, 132, 135, 137B, 139, 141, 142, 146, 148, 149, 150, 151, 152, 153, 160, 161, 162, 171, 173, 174, 176, 177, 182, 183)
Drugi	Adrenomedulin • Mirisni • Opsin (3, 4, 5, 1LW, 1MW, 1SW, RGR, RRH) • Proteazom-aktivirani (1, 2, 3, 4) • SREB (1, 2, 3)

Klasa B: Sekretinu slični

Orfan

GPR (56, 64, 97, 98, 110, 111, 112, 113, 114, 115, 116, 123, 124, 125, 126, 128, 133, 143, 144, 155, 157)

Drugi

Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2)

Klasa C: Metabotropni
glutamat / feromon

Ukus	TAS1R (1, 2, 3) • TAS2R (1, 3, 4, 5, 8, 9, 10, 12, 13, 14, 16, 19, 20, 30, 31, 38, 39, 40, 41, 42, 43, 45, 46, 50)
Drugi	Kalcijum-detektujući receptor • GABA B (1, 2) • Glutamatni receptor (Metabotropni glutamat (1, 2, 3, 4, 5, 6, 7, 8)) • GPRC6A • GPR (156, 158, 179) • RAIG (1, 2, 3, 4)

Klasa F:
Frizzled / Zaglađeni

Uvojiti	Frizzled (1, 2, 3, 4, 5, 6, 7, 8, 9, 10)
Zaglađeni	Zaglađeni

B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)

Read other articles:

Famiglia di lanciatori Thor

Questa voce o sezione sull'argomento astronautica non cita le fonti necessarie o quelle presenti sono insufficienti. Puoi migliorare questa voce aggiungendo citazioni da fonti attendibili secondo le linee guida sull'uso delle fonti. Segui i suggerimenti del progetto di riferimento. Thor-Able pronto per il lancio del Pioneer 1. Thor è una famiglia di razzi vettore utilizzati dalla NASA e derivati dal missile balistico PGM-17 Thor. Partendo dal primo lanciatore, il Thor-Able, questa fami...

Elevation (album Anggun)

ElevationAlbum studio karya AnggunDirilis2008Direkam2007–2008GenreUrban, hip-hopLabelHeben Music, Warner, Sony MusicProduserTefa & MastaKronologi Anggun Best-Of(2006)Best-Of2006 Elevation(2008) Echoes(2011)Echoes2011 Sampul alternatif Elevation adalah album studio internasional keempat oleh penyanyi Indonesia Anggun C. Sasmi. Album ini dirilis pada akhir tahun 2008. Album ini terasa sangat berbeda dengan album-album Anggun sebelumnya yang didominasi nuansa World Music dan etnik. Ham...

Bandar Udara Novy Khabarovsk

Bandar Udara Novy KhabarovskIATA: KHVICAO: UHHHInformasiJenisPublikPemilikGovernment of the Khabarovsky RegionPengelolaJSC Khabarovsk AirportMelayaniKhabarovskLokasiKhabarovsk, RusiaMaskapai penghubung Aurora Khabarovsk Airlines S7 Airlines Vostok Aviation Company Yakutia Airlines Nordwind Airlines Pegas Fly Ketinggian dpl74 mdplKoordinat48°31′41″N 135°11′18″E / 48.52806°N 135.18833°E / 48.52806; 135.18833Koordinat: 48°31′41″N 135°11′18″...

Jwauijeong

JwauijeongLukisan Ha Yeon yang menjabat sebagai Jwauijeong selama masa pemerintahan Raja Sejong.Nama KoreaHangul좌의정/ 좌상/ 좌정승/ 좌규/ 좌합/ 좌대 Hanja左議政/ 左相/ 左政丞/ 左揆/ 左閤/ 左臺 Alih AksaraJwauijeong[1]/ Jwasang / Jwajeongseung / Jwagyu / Jwahap / JwadaeMcCune–Reischauerchwaŭijŏng / chwasang/ chwakyu / chwahap / chwadae Jwauijeong [tɕwa ɰi tɕʌŋ] adalah Kanselir Negara Kedua[1][2] dari Uijeongbu (Dewan Negara), perin...

جمهورية ليتوانيا الاشتراكية السوفيتية

55°30′N 24°00′E / 55.500°N 24.000°E / 55.500; 24.000 Lithuania SSR جمهورية ليتوانيا الاشتراكية السوفيتية Lithuania Soviet Socialist Republic 1940 – 1991 جمهورية ليتوانيا الاشتراكية السوفيتيةعلم جمهورية ليتوانيا الاشتراكية السوفيتيةشعار يا عمال العالم اتحدوا النشيد : عاصمة فيلنيوس نظام الح�...

Ministère de l'Économie, du Commerce et de l'Industrie

Pour les articles homonymes, voir METI (homonymie). Cet article est une ébauche concernant l’économie et le Japon. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Ministère de l'Économie, du Commerce et de l'Industrie(ja) 経済産業省Keizai-sangyō-shōHistoireFondation 6 janvier 2001Prédécesseur Ministère du commerce international et de l'industrie (en)CadreSigle (en) METIType Ministère japona...

Jim Traber

American baseball player Baseball player Jim TraberFirst basemanBorn: (1961-12-26) December 26, 1961 (age 62)Columbus, Ohio, U.S.Batted: LeftThrew: LeftProfessional debutMLB: September 21, 1984, for the Baltimore OriolesNPB: April 8, 1990, for the Kintetsu BuffaloesLast appearanceMLB: October 1, 1989, for the Baltimore OriolesNPB: October 10, 1991, for the Kintetsu BuffaloesMLB statisticsBatting average.227Home runs27Runs batted...

Gander International Airport

Airport in Newfoundland and Labrador, Canada Gander International AirportIATA: YQXICAO: CYQXWMO: 71803SummaryAirport typePublicOwnerTransport Canada[1]OperatorGander International Airport AuthorityServesGander, Newfoundland and LabradorTime zoneNST (UTC−03:30) • Summer (DST)NDT (UTC−02:30)Elevation AMSL496 ft / 151 mCoordinates48°56′51″N 54°33′36″W / 48.94750°N 54.56000°W / 48.94750; -54.56000Websitewww.ganderairport.c...

Skuldelev ships

Viking ships recovered from Peberrenden The placement of the Skuldelev ships before excavation. The Skuldelev ships are five original Viking ships recovered from the waterway of Peberrenden at Skuldelev, c. 20 km (12 mi) north of Roskilde in Denmark. In 1962, the remains of the submerged ships were excavated in the course of four months. The recovered pieces constitute five types of Viking ships and have all been dated to the 11th century. They are thought to have been an earl...

2020年夏季奧林匹克運動會波蘭代表團

2020年夏季奥林匹克运动会波兰代表團波兰国旗IOC編碼POLNOC波蘭奧林匹克委員會網站olimpijski.pl（英文）（波兰文）2020年夏季奥林匹克运动会（東京）2021年7月23日至8月8日（受2019冠状病毒病疫情影响推迟，但仍保留原定名称）運動員206參賽項目24个大项旗手开幕式：帕维尔·科热尼奥夫斯基（游泳）和马娅·沃什乔夫斯卡（自行车）[1]闭幕式：卡罗利娜·纳亚（皮划艇）&#...

Walter Long, 1st Viscount Long

British politician (1854–1924) The Right HonourableThe Viscount LongPC JP FRSSecretary of State for the ColoniesIn office10 December 1916 – 10 January 1919MonarchGeorge VPrime MinisterDavid Lloyd GeorgePreceded byBonar LawSucceeded byThe Viscount MilnerFirst Lord of the AdmiraltyIn office10 January 1919 – 13 February 1921MonarchGeorge VPrime MinisterDavid Lloyd GeorgePreceded bySir Eric GeddesSucceeded byThe Viscount Lee of Fareham2nd Leader of the Ulster Union...

Edoardo Amaldi

Edoardo Amaldi (1960) BiografiKelahiran5 September 1908 Carpaneto Piacentino Kematian5 Desember 1989 (81 tahun)Roma Tempat pemakamanCampo Verano Galat: Kedua parameter tahun harus terisi! Data pribadiPendidikanUniversitas Roma La Sapienza KegiatanSpesialisasiFisika Pekerjaanfisikawan, dosen Bekerja diUniversitas Roma La Sapienza KeluargaPasangan nikahGinestra Giovene AnakUgo Amaldi, Daniela Amaldi AyahUgo Amaldi Penghargaan(25 April 1968) Foreign Member of the Royal Society ...

Сборная Аргентины по футболу

Сборная Аргентины Прозвище La Albiceleste (с исп. — «Бело-голубые») Конфедерация КОНМЕБОЛ (Южная Америка) Федерация Ассоциация футбола Аргентины Главный тренер Лионель Скалони Капитан Лионель Месси Наибольшеекол-во игр Лионель Месси (180)[1] Лучший бомбардир Лионе�...

Pompeys Pillar National Monument

Rock formation in Montana, USA Pompeys Pillar National MonumentLocationYellowstone County, Montana, USANearest cityBillings, MTCoordinates45°59′43″N 108°00′21″W / 45.99528°N 108.00583°W / 45.99528; -108.00583Area51 acres (21 ha)[1]EstablishedJanuary 17, 2001Visitors50,000 (in 2002)Governing bodyU.S. Bureau of Land ManagementWebsitePompeys Pillar National Monument Pompeys Pillar National Monument is a rock formation located in...

مكتب بنغلاديش للإحصاء

مكتب بنغلاديش للإحصاء (بالإنجليزية: Bangladesh Bureau of Statistics)‏، و(بالبنغالية: বাংলাদেশ পরিসংখ্যান ব্যুরো)‏ مكتب بنغلاديش للإحصاء تفاصيل الوكالة الحكومية البلد بنغلاديش تأسست 1974 المركز دكا الإدارة موقع الويب الموقع الرسمي تعديل مصدري - تعديل مك�...

Rodrigo López (footballer, born 1978)

Uruguayan footballer This article includes a list of general references, but it lacks sufficient corresponding inline citations. Please help to improve this article by introducing more precise citations. (August 2018) (Learn how and when to remove this message) Rodrigo López López in 2015Personal informationFull name Hernán Rodrigo López MoraDate of birth (1978-01-21) 21 January 1978 (age 46)Place of birth Montevideo, UruguayHeight 1.81 m (5 ft 11 in)Position(s) Centre...

Prepuzio clitorideo

Prepuzio clitorideoLa figura mostra il cappuccio della clitoride 1. monte di Venere 2. prepuzio clitorideo 3. clitoride 4. grandi labbra 5. piccole labbra 6. perineo IdentificatoriTAA09.2.01.009 FMA20169 Modifica dati su Wikidata · Manuale Nell'anatomia femminile il prepuzio clitorideo, chiamato anche cappuccio della clitoride, è una parte esterna della clitoride. Indice 1 Anatomia 2 Bibliografia 3 Voci correlate 4 Altri progetti Anatomia Si trova sotto la commessura labiale super...

Mark Knopfler

British musician (born 1949) Knopfler redirects here. For his brother, see David Knopfler. Mark KnopflerOBEKnopfler performing in 2015Background informationBirth nameMark Freuder KnopflerBorn (1949-08-12) 12 August 1949 (age 74)Glasgow, ScotlandOriginBlyth, Northumberland, EnglandGenres Rock roots rock Celtic rock blues rock country rock Occupation(s)Musiciansingersongwriterrecord producerInstrument(s)GuitarvocalsYears active1965–presentLabelsVertigoMercuryWarner Bros.RepriseVerveVirgi...

Statewide opinion polling for the 2008 Republican Party presidential primaries

2008 U.S. presidential election Timeline General election debates National polling Statewide polling Parties Democratic Party Candidates Debates and forums Primaries National polling Statewide polling Results Nominee Convention superdelegates Republican Party Candidates Debates and forums Primaries National polling Statewide polling Results Nominee Convention Minor parties Libertarian Party primaries convention Green Party primaries convention Constitution Party All candidates Related races ...

Washington Ellsworth Lindsey

3rd Governor of New Mexico Washington Ellsworth Lindsey3rd Governor of New MexicoIn officeFebruary 18, 1917 – January 1, 1919LieutenantVacantPreceded byEzequiel Cabeza De BacaSucceeded byOctaviano Ambrosio Larrazolo2nd Lieutenant Governor of New MexicoIn officeJanuary 1, 1917 – February 18, 1917GovernorEzequiel Cabeza de BacaPreceded byEzequiel Cabeza de BacaSucceeded byBenjamin F. Pankey Personal detailsBornDecember 20, 1862Armstrongs Mills, OhioDiedApril 5, 192...