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G protein-spregnuti receptor 17
G protein-spregnuti receptor 17
Identifikatori
Simboli	GPR17; DKFZp686M18273
Vanjski ID	OMIM: 603071 MGI: 3584514 HomoloGene: 83191 IUPHAR: GPR17 GeneCards: GPR17 Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu-sličnog receptora; • receptorska aktivnost; • aktivnost hemokinskog receptora; • aktivnost purinergijskog nukleotidnog receptora, G-protein spregnutog;
Celularna komponenta	• integralno sa ćelijskom membranom; • membrana;
Biološki proces	• prenos signala; • signalni put G-protein spregnutog receptora;
Pregled RNK izražavanja
	podaci
Ortolozi
Vrsta	Čovek
Entrez	2840
Ensembl	ENSG00000144230
UniProt	Q13304
RefSeq (mRNA)	NM_005291
RefSeq (protein)	NP_005282
Lokacija (UCSC)	Chr 2:; 128.12 - 128.13 Mb
PubMed pretraga	[1]

GPR17, Uracil nukleotidni/cisteinil leukotrienski receptor, je protein koji je kod čoveka kodiran GPR17 genom.^[1]^[2]

Vidi još

Leukotrien

Literatura

^ Raport CJ, Schweickart VL, Chantry D, Eddy RL Jr, Shows TB, Godiska R, Gray PW (1996). „New members of the chemokine receptor gene family”. J Leukoc Biol. 59 (1): 18—23. PMID 8558062.
^ „Entrez Gene: GPR17 G protein-coupled receptor 17”.

Dodatna literatura

Macrez-Leprêtre N; Kalkbrenner F; Morel JL; et al. (1997). „G protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes.”. J. Biol. Chem. 272 (15): 10095—102. PMID 9092554. doi:10.1074/jbc.272.15.10095.
Bläsius R, Weber RG, Lichter P, Ogilvie A (1998). „A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21.”. J. Neurochem. 70 (4): 1357—65. PMID 9523551. doi:10.1046/j.1471-4159.1998.70041357.x.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Rual JF; Venkatesan K; Hao T; et al. (2005). „Towards a proteome-scale map of the human protein-protein interaction network.”. Nature. 437 (7062): 1173—8. PMID 16189514. doi:10.1038/nature04209.
Ciana P; Fumagalli M; Trincavelli ML; et al. (2006). „The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.”. EMBO J. 25 (19): 4615—27. PMC 1589991 . PMID 16990797. doi:10.1038/sj.emboj.7601341.
M. Kandhavelu, M. P. Abbracchio, P. Angeli, M. Buccioni, D. Dal Ben, C. Lammi, D. Lecca, G. Marucci, G. Cristalli. “Site directed mutagenesis of GPR17 receptor” 16th Camerino-Noordwijkerhout Symposium “An Overview on Receptor Chemistry, Camerino, September 9-13,P28, 2007.http://www.unicam.it/farmacia/symposium/abstracts.htm}-