G protein spregnuti receptor, familija C, grupa 5, član C je protein koji je kod ljudi kodiran GPRC5Cgenom.[1][2]
Ovaj protein pripada familiji tipa 3 G protein spregnutih receptora, koja ima karakteristični 7-transmembranski domen. On potencijalno učestvuje u interakciji između retinoidne kiseline i G protein signalnih puteva. Retinoinska kiselina ima kritičnu ulogu u razvoju, ćelijskom rastu, i diferencijaciji. Ovaj gen potencijalno učestvuje u embrionskom razvoju i diferencijaciji epitelnih ćelija.[2]
Reference
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Maruyama K, Sugano S (1994). „Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1–2): 171—4. PMID8125298. doi:10.1016/0378-1119(94)90802-8.
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Bräuner-Osborne H, Jensen AA, et al. (2001). „Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D”. Biochim. Biophys. Acta. 1518 (3): 237—48. PMID11311935.
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Ota T, Suzuki Y, et al. (2004). „Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40—5. PMID14702039. doi:10.1038/ng1285.
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Otsuki T, Ota T, et al. (2007). „Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries”. DNA Res. 12 (2): 117—26. PMID16303743. doi:10.1093/dnares/12.2.117.
„GPRC5 Receptors: RAIG3”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано из оригинала 04. 03. 2016. г.
