PROFILPELAJAR.COM

G protein spregnuti receptor 156
G protein spregnuti receptor 156
Identifikatori
Simboli	GPR156; GABABL; PGR28
Vanjski ID	OMIM: 610464 MGI: 2653880 HomoloGene: 17683 IUPHAR: GPR156 GeneCards: GPR156 Gene
Ontologija gena
Molekularna funkcija	• aktivnost G-protein spregnutog GABA receptora;
Celularna komponenta	• ćelijska membrana; • integralno sa membranom;
Biološki proces	• prenos signala; • signalni put G-protein spregnutog receptor;
Pregled RNK izražavanja
	podaci
Ortolozi
Vrsta	Čovek
Entrez	165829
Ensembl	ENSG00000175697
UniProt	Q8NFN8
RefSeq (mRNA)	NM_001168271.1
RefSeq (protein)	NP_001161743.1
Lokacija (UCSC)	Chr 3:; 119.88 - 120 Mb
PubMed pretraga	[1]

GPR156 (G protein spregnuti receptor 156) je ljudski gen koji kodira G protein spregnuti receptor iz familije metabotropnih glutamatnih receptora.^[1] Po homologiji sekvence ovaj gen je moguća podjedinica GABA_B receptora, međutim kad je izražen u ćelijama sam ili sa drugim GABA_B podjedinicama, on je manifestuje respons na GABA_B ligande. Funkcija ovog gena do sad nije razjašnjena.^[2]

Reference

^ „Entrez Gene: GPR156 G protein-coupled receptor 156”.
^ Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN (2003). „Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor”. Brain Res. Mol. Brain Res. 110 (2): 305—17. PMID 12591167. doi:10.1016/S0169-328X(02)00662-9.

Literatura

Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Calver AR; Michalovich D; Testa TT; et al. (2003). „Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor.”. Brain Res. Mol. Brain Res. 110 (2): 305—17. PMID 12591167. doi:10.1016/S0169-328X(02)00662-9.
Vassilatis DK; Hohmann JG; Zeng H; et al. (2003). „The G protein-coupled receptor repertoires of human and mouse.”. Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903—8. PMC 153653 . PMID 12679517. doi:10.1073/pnas.0230374100.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.

[entrez-1] „Entrez Gene: GPR156 G protein-coupled receptor 156”.

[pmid12591167-2] Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN (2003). „Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor”. Brain Res. Mol. Brain Res. 110 (2): 305—17. PMID 12591167. doi:10.1016/S0169-328X(02)00662-9.

[1]

[2]