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G protein-spregnuti receptor 61
G protein-spregnuti receptor 61
Identifikatori
Simboli	GPR61; BALGR; GPCR3
Vanjski ID	OMIM: 606916 MGI: 2441719 HomoloGene: 12910 IUPHAR: GPR61 GeneCards: GPR61 Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu sličnog receptora; • receptorska aktivnost;
Celularna komponenta	• integralno sa ćelijskom membranom; • membrana; • integralno sa membranom;
Biološki proces	• prenos signala; • signalni put G-protein spregnutog receptora; • biološki_proces;
Ortolozi
Vrsta	Čovek
Entrez	83873
Ensembl	ENSG00000156097
UniProt	Q9BZJ8
RefSeq (mRNA)	NM_031936
RefSeq (protein)	NP_114142
Lokacija (UCSC)	Chr 1:; 109.88 - 109.89 Mb
PubMed pretraga	[1]

GPR61, G protein-spregnuti receptor 61, je protein koji je kod čoveka kodiran GPR61 genom.^[1]^[2]^[3]

Ovaj gen pripada familiji G-protein spregnutih receptora. Oni sadrže sedam transmembranskih domena i prenose ekstracelularne signale uz pomoć heterotrimernih G proteina. Protein kodiran ovim genom je blisko srodan receptorima biogenih amina.^[3]

Literatura

^ Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (2001). „Identification of four novel human G protein-coupled receptors expressed in the brain”. Brain Res Mol Brain Res. 86 (1–2): 13—22. PMID 11165367. doi:10.1016/S0169-328X(00)00242-4.
^ Cikos S, Gregor P, Koppel J (2001). „Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain”. Biochim Biophys Acta. 1521 (1–3): 66—72. PMID 11690637. doi:10.1016/s0167-4781(01)00289-5.
^ ^а ^б „Entrez Gene: GPR61 G protein-coupled receptor 61”.

Dodatna literatura

Gregory SG; Barlow KF; McLay KE; et al. (2006). „The DNA sequence and biological annotation of human chromosome 1.”. Nature. 441 (7091): 315—21. PMID 16710414. S2CID 4431933. doi:10.1038/nature04727.
Kimura K; Wakamatsu A; Suzuki Y; et al. (2006). „Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.”. Genome Res. 16 (1): 55—65. PMC 1356129 . PMID 16344560. doi:10.1101/gr.4039406.
Conner AC; Hay DL; Simms J; et al. (2005). „A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors.”. Mol. Pharmacol. 67 (1): 20—31. PMID 15615699. doi:10.1124/mol.67.1. Проверите вредност параметра |doi= (помоћ).
Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899 .
Takeda S; Kadowaki S; Haga T; et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1–3): 97—101. PMID 12044878. S2CID 7116392. doi:10.1016/S0014-5793(02)02775-8.