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G protein-spregnuti receptor 148
G protein-spregnuti receptor 148
Identifikatori
Simboli	GPR148; BTR; PGR6
Vanjski ID	IUPHAR: GPR148 GeneCards: GPR148 Gene
Ontologija gena
Molekularna funkcija	• aktivnost rodopsinu sličnog receptora; • receptorska aktivnost;
Celularna komponenta	• integralno sa ćelijskom membranom; • membrana;
Biološki proces	• prenos signal; • signalni put G-protein spregnutog receptora;
Ortolozi
Vrsta	Čovek
Entrez	344561
Ensembl	ENSG00000173302
UniProt	Q8TDV2
RefSeq (mRNA)	NM_207364
RefSeq (protein)	NP_997247
Lokacija (UCSC)	Chr 2:; 131.2 - 131.2 Mb
PubMed pretraga	[1]

GPR148, G protein-spregnuti receptor 148, je protein koji je kod čoveka kodiran GPR148 genom.^[1] On je prvenstveno izražen u nervnom sistemu i testisima. Pretpostavlja de učestvuje u razvoju raka prostate.

Literatura

^ „Entrez Gene: GPR148 G protein-coupled receptor 148”.

Dodatna literatura

Takeda S; Kadowaki S; Haga T; et al. (2002). „Identification of G protein-coupled receptor genes from the human genome sequence.”. FEBS Lett. 520 (1-3): 97—101. PMID 12044878. doi:10.1016/S0014-5793(02)02775-8.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Vassilatis DK; Hohmann JG; Zeng H; et al. (2003). „The G protein-coupled receptor repertoires of human and mouse.”. Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4903—8. PMC 153653 . PMID 12679517. doi:10.1073/pnas.0230374100.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Parmigiani RB; Magalhães GS; Galante PA; et al. (2005). „A novel human G protein-coupled receptor is over-expressed in prostate cancer.”. Genet. Mol. Res. 3 (4): 521—31. PMID 15688318.
Gloriam DE, Schiöth HB, Fredriksson R (2005). „Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship.”. Biochim. Biophys. Acta. 1722 (3): 235—46. PMID 15777626. doi:10.1016/j.bbagen.2004.12.001.

[entrez-1] „Entrez Gene: GPR148 G protein-coupled receptor 148”.

[1]