Nitrazepam

Nitrazepam
(IUPAC) ime
7-nitro-5-fenil-2,3-dihidro-1H-1,4-benzodiazepin-2-on
Klinički podaci
Robne marke Alodorm, Apo-nitrazepam tablets BP, Apodorm, Benzalin
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 146-22-5
ATC kod N05CD03 , N05CD02
PubChem[1][2] 4506
DrugBank DB01595
ChemSpider[3] 4350
KEGG[4] C07487 DaY
Hemijski podaci
Formula C15H11N3O3 
Mol. masa 281.2661
SMILES eMolekuli & PubHem
Fizički podaci
Tačka topljenja 225 °C (437 °F)
Farmakokinetički podaci
Poluvreme eliminacije 15-38 sati
Farmakoinformacioni podaci
Trudnoća ?
Pravni status
Način primene Oralno

Nitrazepam je benzodiazepinski derivat koji se koristi kao antikonvulsant i hipnotik.[5][6][7][8][9][10][11]

Reference

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Rickels K: The clinical use of hypnotics: indications for use and the need for a variety of hypnotics. Acta Psychiatr Scand Suppl. 1986;332:132-41. PMID 2883820
  6. Robertson MD, Drummer OH: Postmortem drug metabolism by bacteria. J Forensic Sci. 1995 May;40(3):382-6. PMID 7782744
  7. Oelschlager H: [Chemical and pharmacologic aspects of benzodiazepines] Schweiz Rundsch Med Prax. 1989 Jul 4;78(27-28):766-72. PMID 2570451
  8. Podhorna J, Krsiak M: Behavioural effects of a benzodiazepine receptor partial agonist, Ro 19-8022, in the social conflict test in mice. Behav Pharmacol. 2000 Apr;11(2):143-51. PMID 10877119
  9. Nowakowska E, Chodera A: Studies on the involvement of opioid mechanism in the locomotor effects of benzodiazepines in rats. Pharmacol Biochem Behav. 1991 Feb;38(2):265-6. PMID 1676167
  10. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682. 
  11. Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412. 

Spoljašnje veze

Read other articles:

Grand Prix Sepeda Motor F.I.M. musim 2018 Sebelum: 2017 Sesudah: 2019 Moto2 musim 2018Moto3 musim 2018 Marc Márquez adalah Juara MotoGP 2018. Kejuaraan Dunia FIM MotoGP 2018 adalah musim Kejuaraan Dunia F.I.M. Road Racing ke-70. Marc Márquez memasuki musim sebagai juara bertahan, dengan Repsol Honda menjadi juara bertahan tim dan Honda sebagai juara bertahan konstruktor. Awalnya dijadwalkan untuk 19 balapan, musim ini dikurangi satu Grand Prix karena pembatalan Grand Prix Silverstone 26 Agu...

Mauricio FunesPresiden El SalvadorMasa jabatan1 Juni 2009 – 1 Juni 2014Wakil PresidenSalvador Sánchez CerénPendahuluAntonio SacaPenggantiSalvador Sánchez Cerén Informasi pribadiLahir18 Oktober 1959 (umur 64)San Salvador, El SalvadorPartai politikFrente Farabundo Martí para la Liberación NacionalSuami/istriWanda PignatoSunting kotak info • L • B Carlos Mauricio Funes Cartagena (lahir 18 Oktober 1959) adalah Presiden El Salvador. Ia memenangkan Pemilihan Umum...

Untuk kegunaan lain, lihat Kalush (disambiguasi). KalushKalush pada tahun 2022.Informasi latar belakangNama lainKalush OrchestraAsalUkrainaGenrefolk rock dan rapTahun aktif2019–sekarangLabelDef Jam RecordingsArtis terkaitAlyona AlyonaGo_AJerry HeilKhrystyna SoloviyOkean ElzySkofka [uk]YarmakAnggota Oleh Psiuk Ihor Didenchuk [uk] Vlad Kurochka (KylymMen) Templat:8px Kalush Orchestra: Tymofii Muzychuk Vitalii Duzhyk Sasha Tab Mantan anggota Danyil Chernov (KylymMen)&...

Alexander AlekhineNama lengkapAlexander Alexandrovich AlekhineAsal negaraKekaisaran Rusia → Soviet Rusia (sebelum 1921)Prancis (setelah 1924)Lahir(1892-10-31)31 Oktober 1892Moscow, Kekaisaran RusiaMeninggal24 Maret 1946(1946-03-24) (umur 53)Estoril, PortugalJuara Dunia1927–19351937–1946 Alexander Alexandrovich Alekhine (Bahasa Rusia: Александр Александрович Алéхин; 31 Oktober 1892 – 24 Maret 1946) adalah grandmaster catur R...

Klaten beralih ke halaman ini. Untuk ibukota kabupaten, lihat Klaten (kota). Kabupaten KlatenKabupatenTranskripsi bahasa daerah • Hanacarakaꦏ꧀ꦭꦛꦺꦤ꧀Candi Plaosan Lor LambangMotto: Tumenga tata anggatra rahardja(Jawa) Menatap keharmonisan demi membangun kesejahteraan(1950 Masehi)PetaKabupaten KlatenPetaTampilkan peta JawaKabupaten KlatenKabupaten Klaten (Indonesia)Tampilkan peta IndonesiaKoordinat: 7°41′00″S 110°37′00″E / 7.6833°S 1...

Обсерватория имени Штефаникачеш. Štefánikova hvězdárna Тип астрономическая обсерватория Код 541 Расположение Прага (Чехия) Координаты 50°04′52″ с. ш. 14°23′54″ в. д.HGЯO Высота 321 м Дата открытия 1928 Сайт planetum.cz/stefanikova-… Обсерватория Штефаник — астрономическая обсервато�...

Genus of fungi Mycopan Mycopan scabripes Scientific classification Domain: Eukaryota Kingdom: Fungi Division: Basidiomycota Class: Agaricomycetes Order: Agaricales Family: Porotheleaceae Genus: MycopanRedhead, Moncalvo & Vilgalys (2013) Type species Mycopan scabripes(Murrill) Redhead, Moncalvo & Vilgalys (2013) Synonyms[1] Mycena scabripes (Murrill) Murrill (1916) Prunulus scabripes Murrill (1916) Hydropus scabripes (Murrill) Singer (1962) Mycopan is one of several genera of a...

This article may require cleanup to meet Wikipedia's quality standards. The specific problem is: poor grammar. Please help improve this article if you can. (May 2022) (Learn how and when to remove this template message) Political party in Sri Lanka United People's Power සමගි ජනබලවේගයஐக்கிய மக்கள் சக்திAbbreviationSJBLeaderSajith PremadasaChairmanSarath FonsekaSecretaryRanjith MaddumabandaraSpokesmanS.M. Marikkar[1]FounderSa...

Nay Myo WaiBorn (1972-07-22) 22 July 1972 (age 51)NationalityMyanmarEducationB.E (Aeronautical)OccupationPoliticianPolitical partyPeace and Diversity PartyParentHla Myint (father) Nay Myo Wai (Burmese: နေမျိုးဝေ; born 22 July 1972) is a Burmese nationalist politician and a land activist. He is the chairman of Peace and Diversity Party from Myanmar.[1] Political ideology Nay Myo Wai claims that he advocates a form of nationalism which aims to avoid an ideology ba...

See also: Bryan Adams discography Bryan Adams video discographyVideo albums9Music videos40 The videography of Canadian rock musician Bryan Adams consists of four video albums and 40 music videos. Videos Year Video details Certifications 1984 Reckless Released:, 1984 Label: A&M Format: VHS 1992 Waking Up The Neighbours Released: 1992 Label: A&M Format: VHS 1994 So Far So Good (And More) Released: 1994 Label: A&M Format: VHS UK: Gold[1] 1997 MTV Unplugged Released: December ...

A descendant of Mandalay Thabin The Mandalay Thabin (Burmese: မန္တလေးသဘင်) refers to the Mandalay-based dramatic arts industry, including yoke thé, anyeint, zat pwe, etc., flourished since the late Konbaung era, during the reigns of King Mindon and King Thibaw.[1] At first, Mandalay Thabin could be distinguished into Amyint Thabin (High Drama), which could be performed on a raised stage, including yoke thé and royal court dramas and Anyeint Thabin (Low Drama), ...

Mujer con mantón de Manila by the Filipino painter Juan Luna (c. 1880s) The Manila shawl (Spanish: mantón de Manila or mantón de seda) is an embroidered silk shawl derived from the Filipino pañuelo. They were popular in the Philippines, Latin America , and Spain during the colonial era. It also became popular in European fashions in the 19th century. In modern times, it is still an aspect of various traditional clothing in Hispanic cultures and is particularly prominent as part of the cos...

United States historic placeHulett FarmU.S. National Register of Historic Places Show map of VermontShow map of the United StatesLocationUS 7, Wallingford, VermontCoordinates43°26′1″N 72°59′28″W / 43.43361°N 72.99111°W / 43.43361; -72.99111Area5 acres (2.0 ha)Built1810 (1810)Architectural styleFederalMPSRural Otter Creek Valley MRANRHP reference No.86003220[1]Added to NRHPNovember 26, 1986 The Hulett Farm is a historic farms...

Emu Bottom Homestead is a historic homestead near Sunbury, Victoria, Australia. Built c. 1836, Emu Bottom is the oldest existing farmhouse constructed by settlers in Victoria.[1][2] It was so named because it was low lying ground and the haunt of numerous emus.[3] The main homestead and some of its outlying buildings were constructed from local stone, dry coursed with creek mud.[4] Emu Bottom is also a rare example of early Australian colonial architecture, wit...

Means of distributing alternating-current electrical power This article is about electrical power distribution. For the signal processing concept with the same name, see Polyphase matrix. One voltage cycle of a three-phase system A polyphase system (the term coined by Silvanus Thompson) is a means of distributing alternating-current (AC) electrical power that utilize more than one AC phase, which refers to the phase offset value (in degrees) between AC in multiple conducting wires; phases may...

1983 novel by John M. Ford The Dragon Waiting AuthorJohn M. FordCountryUnited StatesLanguageEnglishGenreHistorical fantasyPublisherTimescape BooksPublication date1983Media typePrint (hardcover, paperback)Pages365ISBN0-671-47552-5 The Dragon Waiting: A Masque of History is a 1983 historical fantasy novel by American writer John M. Ford. It won the 1984 World Fantasy Award for Best Novel. This book, set in an alternate history, contains such plot elements as vampirism, the House of Medici,...

Agenzia Europea per la difesa Affiliazione internazionaleUnione europea eccetto la Danimarca Fondazione12 luglio 2004 Scoposupportare gli stati membri ed il Consiglio nel loro sforzo di migliorare le capacità difensive europee nel campo della gestione delle crisi e sostenga la politica europea di sicurezza e di difesa com'è ora e come si svilupperà nel futuro. Sede centrale Bruxelles IndirizzoRue des Drapiers 17-23, 1050 Ixelles Presidente Josep Borrell Direttore Jorge Domecq Bilancio31 mi...

Australian rules footballer Australian rules footballer Lewis Jetta Jetta playing for West Coast in July 2019Personal informationFull name Lewis JettaDate of birth (1989-05-04) 4 May 1989 (age 34)Place of birth Bunbury, Western AustraliaOriginal team(s) Swan Districts (WAFL)Draft 14th overall, 2009Sydney SwansHeight 182 cm (6 ft 0 in)Weight 80 kg (176 lb)Position(s) Utility/Half-backPlaying career1Years Club Games (Goals)2010–2015 Sydney 127 (99)2016–202...

Aquaman 2 beralih ke halaman ini. Untuk Iterasi komik Aquaman II, lihat Aquaman § Biografi_karakter_fiksi. Aquaman and the Lost KingdomPoster rilis teaterSutradaraJames WanProduser Peter Safran James Wan Rob Cowan SkenarioDavid Leslie Johnson-McGoldrickCerita James Wan David Leslie Johnson-McGoldrick Jason Momoa Thomas Pa'a Sibbett BerdasarkanKarakterdari DCPemeran Jason Momoa Patrick Wilson Amber Heard Yahya Abdul-Mateen II Randall Park Dolph Lundgren Temuera Morrison Martin Short Nico...

Log pod Mangartom—  așezare umană  —Log pod MangartomLog pod Mangartom (Slovenia)Poziția geograficăCoordonate: 46°24′21.27″N 13°36′11.29″E ({{PAGENAME}}) / 46.4059083°N 13.6031361°EȚară SloveniaRegiune istoricăPrimorskaComunăBovecSuprafață  - Total40,55 km²Altitudine644 m.d.m.Populație  - Total139 locuitoriFus orarCET (+1) - Ora de vară (DST)CEST (+2)Cod...