CDC42EP2

معرفات

CDC42EP2, BORG1, CEP2, CDC42 effector protein 2

معرفات خارجية

الوراثة المندلية البشرية عبر الإنترنت 606132 MGI: MGI:1929744 HomoloGene: 4933 GeneCards: 10435

علم الوجود الجيني
وظائف جزيئية	• ‏GO:0001948، ‏GO:0016582 ربط بروتيني • ‏GO:0005097، ‏GO:0005099، ‏GO:0005100 GTPase activator activity • opioid peptide activity
مكونات خلوية	• سيتوبلازم • microtubule cytoskeleton • غشاء خلوي • غشاء • نظام غشائي داخلي • هيكل خلوي • عصارة خلوية • phagocytic vesicle
عمليات حيوية	• positive regulation of pseudopodium assembly • positive regulation of actin filament polymerization • positive regulation of protein-containing complex assembly • actin cytoskeleton organization • Rho protein signal transduction • actin filament organization • regulation of cell shape • ‏GO:0032320، ‏GO:0032321، ‏GO:0032855، ‏GO:0043089، ‏GO:0032854 positive regulation of GTPase activity • regulation of signaling receptor activity • cellular response to interferon-gamma
المصادر:Amigo / QuickGO

نمط التعبير عن الحمض النووي الريبوزي

المزيد من بيانات التعبير المرجعية

تماثلات متسلسلة

أنواع

الإنسان

الفأر


O14613


Q8JZX9

RefSeq (رنا مرسال.)


‏XM_047426244 NM_006779، ‏XM_047426244


NM_026772

RefSeq (بروتين)


NP_006770


NP_081048

الموقع (UCSC

n/a

Chr 19: 5.97 – 5.97 Mb

بحث ببمد

[1]

[2]

ويكي بيانات

اعرض/عدّل إنسان

اعرض/عدّل فأر

CDC42EP2‏ (CDC42 effector protein 2) هوَ بروتين يُشَفر بواسطة جين CDC42EP2 في الإنسان.^[1]^[2]^[3]

الوظيفة

هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018)

الأهمية السريرية

هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018)

المراجع

^ Hirsch DS، Pirone DM، Burbelo PD (يناير 2001). "A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes". The Journal of Biological Chemistry. ج. 276 ع. 2: 875–83. DOI:10.1074/jbc.M007039200. PMID:11035016.{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link)
^ Joberty G، Perlungher RR، Macara IG (أكتوبر 1999). "The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins". Molecular and Cellular Biology. ج. 19 ع. 10: 6585–97. PMC:84628. PMID:10490598.
^ "Entrez Gene: CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة

Guru SC، Agarwal SK، Manickam P، Olufemi SE، Crabtree JS، Weisemann JM، Kester MB، Kim YS، Wang Y، Emmert-Buck MR، Liotta LA، Spiegel AM، Boguski MS، Roe BA، Collins FS، Marx SJ، Burns L، Chandrasekharappa SC (يوليو 1997). "A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus". Genome Research. ج. 7 ع. 7: 725–35. DOI:10.1101/gr.7.7.725. PMC:310681. PMID:9253601.
Burbelo PD، Snow DM، Bahou W، Spiegel S (أغسطس 1999). "MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts". Proceedings of the National Academy of Sciences of the United States of America. ج. 96 ع. 16: 9083–8. DOI:10.1073/pnas.96.16.9083. PMC:17736. PMID:10430899.
Joberty G، Perlungher RR، Sheffield PJ، Kinoshita M، Noda M، Haystead T، Macara IG (أكتوبر 2001). "Borg proteins control septin organization and are negatively regulated by Cdc42". Nature Cell Biology. ج. 3 ع. 10: 861–6. DOI:10.1038/ncb1001-861. PMID:11584266.
Xue Y، Bi F، Zhang X، Zhang S، Pan Y، Liu N، Shi Y، Yao X، Zheng Y، Fan D (يونيو 2006). "Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation". International Journal of Cancer. ج. 118 ع. 12: 2965–72. DOI:10.1002/ijc.21763. PMID:16395716.

جينات الكروموسوم 11

هذه بذرة مقالة عن بروتين بحاجة للتوسيع. فضلًا شارك في تحريرها.

التصنيفات الطبية	دليل الوراثة المندلية عند البشر (OMIM): 606132
المعرفات الخارجية	Ensembl Transcript ID: ENST00000279249 نظام اللغة الطبية الموحدة (UMLS CUI): C1424136

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