ELP3

ELP3
معرفات
أسماء بديلة ELP3, KAT9, elongator acetyltransferase complex subunit 3
معرفات خارجية الوراثة المندلية البشرية عبر الإنترنت 612722 MGI: MGI:1921445 HomoloGene: 7105 GeneCards: 55140
نمط التعبير عن الحمض النووي الريبوزي
المزيد من بيانات التعبير المرجعية
تماثلات متسلسلة
أنواع الإنسان الفأر
أنتريه 55140 74195
Ensembl ENSG00000134014 ENSMUSG00000022031
يونيبروت
RefSeq (رنا مرسال.)

‏NM_001284222، ‏NM_001284224، ‏NM_001284225، ‏NM_001284226، ‏NM_018091، ‏XM_024447184 NM_001284220، ‏NM_001284222، ‏NM_001284224، ‏NM_001284225، ‏NM_001284226، ‏NM_018091، ‏XM_024447184

‏NM_028811، ‏NR_045599 NM_001253812، ‏NM_028811، ‏NR_045599

RefSeq (بروتين)

‏NP_001271151، ‏NP_001271153، ‏NP_001271154، ‏NP_001271155، ‏NP_060561، ‏XP_006716417، ‏XP_016869093، ‏XP_024302952، ‏XP_024302953 NP_001271149، ‏NP_001271151، ‏NP_001271153، ‏NP_001271154، ‏NP_001271155، ‏NP_060561، ‏XP_006716417، ‏XP_016869093، ‏XP_024302952، ‏XP_024302953

‏NP_083087 NP_001240741، ‏NP_083087

الموقع (UCSC n/a Chr 14: 65.77 – 65.83 Mb
بحث ببمد [1] [2]
ويكي بيانات
اعرض/عدّل إنساناعرض/عدّل فأر

ELP3‏ (Elongator acetyltransferase complex subunit 3) هوَ بروتين يُشَفر بواسطة جين ELP3 في الإنسان.[1][2][3][4][5]

الوظيفة

الأهمية السريرية

المراجع

  1. ^ Creppe C، Malinouskaya L، Volvert ML، Gillard M، Close P، Malaise O، Laguesse S، Cornez I، Rahmouni S، Ormenese S، Belachew S، Malgrange B، Chapelle JP، Siebenlist U، Moonen G، Chariot A، Nguyen L (فبراير 2009). "Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin". Cell. ج. 136 ع. 3: 551–64. DOI:10.1016/j.cell.2008.11.043. PMID:19185337.
  2. ^ Wang YP، Zhou LS، Zhao YZ، Wang SW، Chen LL، Liu LX، Ling ZQ، Hu FJ، Sun YP، Zhang JY، Yang C، Yang Y، Xiong Y، Guan KL، Ye D (يونيو 2014). "Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress". The EMBO Journal. ج. 33 ع. 12: 1304–20. DOI:10.1002/embj.201387224. PMC:4194121. PMID:24769394.
  3. ^ Hawkes NA، Otero G، Winkler GS، Marshall N، Dahmus ME، Krappmann D، Scheidereit C، Thomas CL، Schiavo G، Erdjument-Bromage H، Tempst P، Svejstrup JQ (يناير 2002). "Purification and characterization of the human elongator complex". J Biol Chem. ج. 277 ع. 4: 3047–52. DOI:10.1074/jbc.M110445200. PMID:11714725.{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link)
  4. ^ Okada Y، Yamagata K، Hong K، Wakayama T، Zhang Y (يناير 2010). "A role for the elongator complex in zygotic paternal genome demethylation". Nature. ج. 463 ع. 7280: 554–8. DOI:10.1038/nature08732. PMC:2834414. PMID:20054296.
  5. ^ "Entrez Gene: ELP3 elongation protein 3 homolog (S. cerevisiae)". مؤرشف من الأصل في 2010-12-05.

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