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Kinesin family member 1B
معرفات
أسماء بديلة	kinesin-like protein KIF1B, kinesin superfamily protein KIF1B, KIF1B
معرفات خارجية
تماثلات متسلسلة
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

KIF1B‏ (Kinesin family member 1B) هوَ بروتين يُشَفر بواسطة جين KIF1B في الإنسان.^[1]^[2]^[3]

التفاعل

لقد ثبت أن KIF1B يتفاعل مع GIPC1.^[4]

الأهمية السريرية

هو مرتبط بمرض شاركو-ماري-توث، النوع 2A1.^[5]

المراجع

^ Nagai M، Ichimiya S، Ozaki T، Seki N، Mihara M، Furuta S، Ohira M، Tomioka N، Nomura N، Sakiyama S، Kubo O، Takakura K، Hori T، Nakagawara A (مايو 2000). "Identification of the full-length KIAA0591 gene encoding a novel kinesin-related protein which is mapped to the neuroblastoma suppressor gene locus at 1p36.2". Int J Oncol. ج. 16 ع. 5: 907–16. DOI:10.3892/ijo.16.5.907. PMID:10762626.
^ "Entrez Gene: KIF1B kinesin family member 1B". مؤرشف من الأصل في 2010-03-06.
^ Zhao C، Takita J، Tanaka Y، Setou M، Nakagawa T، Takeda S، Yang HW، Terada S، Nakata T، Takei Y، Saito M، Tsuji S، Hayashi Y، Hirokawa N (يونيو 2001). "Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta". Cell. ج. 105 ع. 5: 587–97. DOI:10.1016/S0092-8674(01)00363-4. PMID:11389829.
^ Bunn، R C؛ Jensen M A؛ Reed B C (أبريل 1999). "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a Link between GLUT1 and the Cytoskeleton". Mol. Biol. Cell. ج. 10 ع. 4: 819–32. DOI:10.1091/mbc.10.4.819. ISSN:1059-1524. PMC:25204. PMID:10198040.
^ "Entrez Gene: KIF1B kinesin family member 1B".

قراءة متعمقة

Nangaku M، Sato-Yoshitake R، Okada Y، وآخرون (1995). "KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria". Cell. ج. 79 ع. 7: 1209–20. DOI:10.1016/0092-8674(94)90012-4. PMID:7528108.
Gong TL، Burmeister M، Lomax MI (1997). "The novel gene D4Mil1e maps to mouse chromosome 4 and human chromosome 1p36". Mamm. Genome. ج. 7 ع. 10: 790–1. DOI:10.1007/s003359900237. PMID:8854876.
Saito M، Hayashi Y، Suzuki T، وآخرون (1998). "Linkage mapping of the gene for Charcot-Marie-Tooth disease type 2 to chromosome 1p (CMT2A) and the clinical features of CMT2A". Neurology. ج. 49 ع. 6: 1630–5. DOI:10.1212/wnl.49.6.1630. PMID:9409358.
Nagase T، Ishikawa K، Miyajima N، وآخرون (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. ج. 5 ع. 1: 31–9. DOI:10.1093/dnares/5.1.31. PMID:9628581.
Bunn RC، Jensen MA، Reed BC (1999). "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a Link between GLUT1 and the Cytoskeleton". Mol. Biol. Cell. ج. 10 ع. 4: 819–32. DOI:10.1091/mbc.10.4.819. PMC:25204. PMID:10198040.
Conforti L، Buckmaster EA، Tarlton A، وآخرون (1999). "The major brain isoform of kif1b lacks the putative mitochondria-binding domain". Mamm. Genome. ج. 10 ع. 6: 617–22. DOI:10.1007/s003359901056. PMID:10341097.
Nagase T، Kikuno R، Ishikawa K، وآخرون (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. ج. 7 ع. 2: 143–50. DOI:10.1093/dnares/7.2.143. PMID:10819331.
Yang HW، Chen YZ، Takita J، وآخرون (2001). "Genomic structure and mutational analysis of the human KIF1B gene which is homozygously deleted in neuroblastoma at chromosome 1p36.2". Oncogene. ج. 20 ع. 36: 5075–83. DOI:10.1038/sj.onc.1204456. PMID:11526494.
Mok H، Shin H، Kim S، وآخرون (2002). "Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins". J. Neurosci. ج. 22 ع. 13: 5253–8. PMID:12097473.
Nakamura N، Miyake Y، Matsushita M، وآخرون (2003). "KIF1Bbeta2, capable of interacting with CHP, is localized to synaptic vesicles". J. Biochem. ج. 132 ع. 3: 483–91. DOI:10.1093/oxfordjournals.jbchem.a003246. PMID:12204119.
Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
Huang YS، Carson JH، Barbarese E، Richter JD (2003). "Facilitation of dendritic mRNA transport by CPEB". Genes Dev. ج. 17 ع. 5: 638–53. DOI:10.1101/gad.1053003. PMC:196011. PMID:12629046.
Chen YY، Takita J، Chen YZ، وآخرون (2004). "Genomic structure and mutational analysis of the human KIF1Balpha gene located at 1p36.2 in neuroblastoma". Int. J. Oncol. ج. 23 ع. 3: 737–44. DOI:10.3892/ijo.23.3.737. PMID:12888911.
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Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
Beausoleil SA، Jedrychowski M، Schwartz D، وآخرون (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 33: 12130–5. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.
Jin J، Smith FD، Stark C، وآخرون (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. ج. 14 ع. 16: 1436–50. DOI:10.1016/j.cub.2004.07.051. PMID:15324660.