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FGF10
بنى متوفرة
بنك بيانات البروتين	Ortholog search: PDBe RCSB
قائمة رموز معرفات بنك بيانات البروتين
	1NUN
معرفات
أسماء بديلة	FGF10, fibroblast growth factor 10
معرفات خارجية	الوراثة المندلية البشرية عبر الإنترنت 602115 MGI: MGI:1099809 HomoloGene: 3284 GeneCards: 2255
علم الوجود الجيني
وظائف جزيئية	• heparin binding; • type 2 fibroblast growth factor receptor binding; • growth factor activity; • ‏GO:0001948، ‏GO:0016582 ربط بروتيني; • fibroblast growth factor receptor binding; • chemoattractant activity; • protein tyrosine kinase activity; • 1-phosphatidylinositol-3-kinase activity; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity;
مكونات خلوية	• الفراغ خارج الخلية; • نواة; • cell surface; • ‏GO:0005578 نسيج بيني خارج الخلية; • غشاء خلوي; • خارج خلوي; • collagen-containing extracellular matrix;
عمليات حيوية	• bud outgrowth involved in lung branching; • limb bud formation; • organ growth; • semicircular canal morphogenesis; • embryonic pattern specification; • bud elongation involved in lung branching; • positive regulation of canonical Wnt signaling pathway; • muscle cell fate commitment; • إفراز الدموع; • positive regulation of Ras protein signal transduction; • positive regulation of urothelial cell proliferation; • regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; • limb development; • radial glial cell differentiation; • female genitalia morphogenesis; • mesonephros development; • odontogenesis of dentin-containing tooth; • prostatic bud formation; • إعادة نمذجة الوعاء الدموي; • regulation of saliva secretion; • توليد الأوعية; • establishment of mitotic spindle orientation; • positive regulation of ERK1 and ERK2 cascade; • embryonic digestive tract morphogenesis; • تشكل العضو الحيواني; • hair follicle morphogenesis; • metanephros development; • lung saccule development; • lung epithelium development; • positive regulation of Notch signaling pathway; • negative regulation of cell population proliferation; • branch elongation involved in salivary gland morphogenesis; • branching involved in salivary gland morphogenesis; • positive regulation of white fat cell proliferation; • bronchiole morphogenesis; • limb morphogenesis; • blood vessel morphogenesis; • lung development; • نمو الغدة الزعترية; • positive regulation of fibroblast proliferation; • negative regulation of cell differentiation; • ERK1 and ERK2 cascade; • positive regulation of epithelial cell migration; • positive regulation of mitotic cell cycle; • spleen development; • smooth muscle cell differentiation; • ‏GO:0060469، ‏GO:0009371 positive regulation of transcription, DNA-templated; • positive regulation of Wnt signaling pathway; • Harderian gland development; • protein localization to cell surface; • respiratory system development; • epidermis development; • positive regulation of peptidyl-tyrosine phosphorylation; • metanephros morphogenesis; • pancreas development; • mammary gland bud formation; • positive chemotaxis; • mesenchymal-epithelial cell signaling involved in lung development; • positive regulation of hair follicle cell proliferation; • lacrimal gland development; • positive regulation of MAPK cascade; • تمايز خلوي; • positive regulation of keratinocyte proliferation; • positive regulation of ATP-dependent activity; • positive regulation of epithelial cell proliferation involved in wound healing; • epithelial cell differentiation; • organ induction; • positive regulation of epithelial cell proliferation; • epidermis morphogenesis; • التئام الجروح; • epithelial cell proliferation; • regulation of activin receptor signaling pathway; • positive regulation of DNA replication; • انجذاب كيميائي; • embryonic genitalia morphogenesis; • salivary gland development; • positive regulation of keratinocyte migration; • response to lipopolysaccharide; • نمو الغدة الدرقية; • keratinocyte proliferation; • semicircular canal fusion; • mammary gland specification; • epithelial cell migration; • white fat cell differentiation; • تنظيم التعبير الجيني; • lung alveolus development; • branching morphogenesis of an epithelial tube; • embryonic digestive tract development; • lung proximal/distal axis specification; • fibroblast growth factor receptor signaling pathway involved in mammary gland specification; • actin cytoskeleton reorganization; • positive regulation of vascular endothelial growth factor receptor signaling pathway; • pituitary gland development; • response to estradiol; • secretion by lung epithelial cell involved in lung growth; • mesenchymal cell differentiation involved in lung development; • lung morphogenesis; • ‏GO:1904578 response to organic cyclic compound; • somatic stem cell population maintenance; • tissue regeneration; • otic vesicle formation; • epithelial cell proliferation involved in salivary gland morphogenesis; • cell-cell signaling; • male genitalia morphogenesis; • ‏GO:1900404 positive regulation of DNA repair; • salivary gland morphogenesis; • MAPK cascade; • embryonic camera-type eye development; • induction of positive chemotaxis; • urothelial cell proliferation; • تشكل العضو الحيواني; • fibroblast growth factor receptor signaling pathway; • regulation of smoothened signaling pathway; • determination of left/right symmetry; • inner ear morphogenesis; • ضبط زيادي للتكاثر الخلوي; • submandibular salivary gland formation; • type II pneumocyte differentiation; • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; • digestive tract development; • regulation of epithelial cell proliferation; • epithelial tube branching involved in lung morphogenesis; • positive regulation of lymphocyte proliferation; • ‏GO:0003257، ‏GO:0010735، ‏GO:1901228، ‏GO:1900622، ‏GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني; • phosphatidylinositol phosphate biosynthetic process; • phosphatidylinositol-3-phosphate biosynthetic process; • peptidyl-tyrosine phosphorylation; • regulation of signaling receptor activity; • positive regulation of protein kinase B signaling; • positive regulation of G1/S transition of mitotic cell cycle;
	المصادر:Amigo / QuickGO
تماثلات متسلسلة
	O15520
	O35565
	‏NM_004465 XM_005248264، ‏NM_004465
	NM_008002
	‏XP_005248321 NP_004456، ‏XP_005248321
	NP_032028
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

FGF10‏ (Fibroblast growth factor 10) هوَ بروتين يُشَفر بواسطة جين FGF10 في الإنسان.^[1]^[2]

الوظيفة

الأهمية السريرية

المراجع

^ Emoto H، Tagashira S، Mattei MG، Yamasaki M، Hashimoto G، Katsumata T، Negoro T، Nakatsuka M، Birnbaum D، Coulier F، Itoh N (سبتمبر 1997). "Structure and expression of human fibroblast growth factor-10". The Journal of Biological Chemistry. ج. 272 ع. 37: 23191–4. DOI:10.1074/jbc.272.37.23191. PMID:9287324.{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link)
^ "Entrez Gene: FGF10 fibroblast growth factor 10". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة

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