Anisodin

Anisodin
(IUPAC) ime
9-metil-3-oksa-9-azatriciklo[3.2.1.02,4]non-7-il α-hidroksi-α-(hidroksimetil)benzeneacetat
Klinički podaci
Identifikatori
CAS broj 52646-92-1
ATC kod nije dodeljen
PubChem[1][2] 4105431
ChemSpider[3] 9791461
Hemijski podaci
Formula C17H21NO5 
Mol. masa 319,35 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Anisodin (daturamin, α-hidroksiskopolamin) je antizpasmodik i antiholinergik koji se koristi za lečenje akutnog cirkulatornog šoka Kini.[4][5] On je tropanski alkaloid i prirodno se javlja u pojedinim vrstama biljki Solanaceae familije.[5] Anisodin deluje kao antagonist muskarinskog acetilholinskog receptora i agonist α1-adrenergičkog receptora.[4]

Povezano

Reference

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. 4,0 4,1 Varma DR, Yue TL (March 1986). „Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats”. British Journal of Pharmacology 87 (3): 587–94. PMC 1916562. PMID 2879586. 
  5. 5,0 5,1 „Dictionary of pharmacological agents - Google Books”. 

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