Dimefox

Dimefox
Names
IUPAC name
N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
Other names
TL-792[1]
T-2002[1]
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.003.706 Edit this at Wikidata
EC Number
  • 204-076-8
KEGG
UNII
  • InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 ☒N
    Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N ☒N
  • InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3
    Key: PGJBQBDNXAZHBP-UHFFFAOYAM
  • CN(C)P(=O)(N(C)C)F
Properties
C4H12FN2OP
Molar mass 154.125 g·mol−1
Appearance colourless liquid
Density 1.11 g·mL–1
14.8 g·L–1
Vapor pressure 14663 mPa
2.28·10–8 atm·m3·mol–1[2]
Pharmacology
inhalation and dermal contact
Legal status
  • UK: Banned
  • US: Banned
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Highly Toxic
GHS labelling:
GHS06: Toxic
Danger
H300, H310
P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, P501
Lethal dose or concentration (LD, LC):
2 mg/kg (oral, mice)[1]
1 mg/kg (oral, rats)[1]
3 mg/kg (intravenous, rabbits)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Dimefox, also known as TL-792 or T-2002, is a highly toxic organophosphate insecticide. In its pure form it is a colourless liquid with a fishy odour.[3] Dimefox was first produced in 1940 by the group of Gerhard Schrader in Germany. It was historically used as a pesticide, but has been deemed obsolete or discontinued for use by the World Health Organization due to being an inhibitor of acetylcholinesterase.[citation needed] It is not guaranteed that all commercial use of this compound ceased, but in most countries[which?] it is no longer registered for use as a pesticide.[4] It is considered an extremely hazardous substance as defined by the United States Emergency Planning and Community Right-to-Know Act.

See also

References

  1. ^ a b c d e Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
  2. ^ "Dimefox".
  3. ^ "IUPAC FOOTPRINT Pesticides Properties Database". Archived from the original on 2011-07-22. Retrieved 2011-04-06.
  4. ^ the WHO recommended classification of pesticides by hazard and guidelines to classification 2009, [1]


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