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MSPI
Names
	Other names MSMPID
Identifiers
CAS Number	70951-04-1;
3D model (JSmol)	Interactive image;
ChemSpider	46405;
PubChem CID	51213;
CompTox Dashboard (EPA)	DTXSID90221186 ;
	InChI InChI=1S/C5H9N2O2PS/c1-6-3-4-7(5-6)10(8,9)11-2/h3-5H,1-2H3 Key: QSLFDILMORXPKP-UHFFFAOYSA-N;
	SMILES C[N+]1=CN(C=C1)P(=O)([O-])SC;
Properties
Chemical formula	C5H9N2O2PS
Molar mass	192.17 g·mol−1
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	3.15 mg/kg (mice, subcutaneous)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

MSPI is an irreversible acetylcholinesterase inhibitor. MSPI reacts with the acetylcholinesterase to form an aged enzyme adduct that can't be reactivated by cholinesterase reactivators.^[1]

References

^ Chabrier, P. E.; Jacob, J. (May 1980). "In vivo and in vitro inhibition of cholinesterase by methyl-1 (S methyl phosphoryl-3) imidazolium (MSPI), a model of an "instantly" aged phosphorylated enzyme". Archives of Toxicology. 45 (1): 15–20. Bibcode:1980ArTox..45...15C. doi:10.1007/BF00303290. PMID 7396718. S2CID 24108114.

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