CS-27349
Chemical compound
Pharmaceutical compound
CS-27349
(1R ,2R ,5S )-8-Methyl-8-azabicyclo[3.2.1]oct-2-yl hydroxy(diphenyl)acetate
CAS Number PubChem CID ChemSpider ChEMBL CompTox Dashboard (EPA ) Formula C 22 H 25 N O 3 Molar mass 351.446 g·mol−1 3D model (JSmol )
CN1C2CC[C@H](C1CC2)OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl
InChI=1S/C22H25NO3/c1-23-18-12-14-19(23)20(15-13-18)26-21(24)22(25,16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-20,25H,12-15H2,1H3/t18?,19?,20-/m1/s1
Key:LSJGAYNIIMEDLR-SOAGJPPSSA-N
CS-27349 , or L -2-α-tropinyl benzilate , is an experimental incapacitating agent . It acts as an antagonist to muscarinic acetylcholine receptors , causing delirium . It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ.[ 1] It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.[ 2]
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