1X2N
5316
18771
ENSG00000160199
ENSMUSG00000006705
P55347Q96I87
O70477
NM_001286258NM_004571NM_001320694NM_197976
NM_016670
NP_001307623.1
NP_057879
PBX/Knotted 1 Homeobox 1 (PKNOX1) is a protein that in humans is encoded by the PKNOX1 gene.[5][6]
An important paralog of this gene is PKNOX2.
PKNOX1 belongs to the three amino acid loop extension (TALE) class of homeodomain transcription factors that form transcriptionally active complexes involved in development and organogenesis. PKNOX1 is essential for embryogenesis, but it can also act as a tumor suppressor in adulthood.[7]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
This article on a gene on human chromosome 21 is a stub. You can help Wikipedia by expanding it.
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