10538
53314
ENSG00000156127
ENSMUSG00000034266
Q16520
O35284
NM_006399
NM_016767
NP_006390
NP_058047
Basic leucine zipper transcription factor, ATF-like, also known as BATF, is a protein which in humans is encoded by the BATF gene.[5][6][7]
The protein encoded by this gene is a nuclear basic leucine zipper (bZIP) protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events.[7]
Mice without the BATF gene (BATF knockout mice) lacked a type of inflammatory immune cell (Th17) and were resistant to conditions that normally induces an autoimmune condition similar to multiple sclerosis.[8]
BATF (gene) has been shown to interact with IFI35.[9]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
This article on a gene on human chromosome 14 is a stub. You can help Wikipedia by expanding it.
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