Duho is a proposed language family of South America, uniting two proposed genetic groupings, Hodi–Saliban^[1] and Ticuna–Yuri. This language family was proposed by Marcelo Jolkesky (2016), based on his previous but now disclaimed Macro-Daha family which had also included the Andoque–Urequena languages.^[2]

Zamponi (2017) concludes that the similarities between Saliban and Hodɨ appear to be due to contact, but that a distant genealogical relationship between Betoi and Sáliban is plausible though not demonstrated. He does not address Ticuna–Yuri.^[3]

Jolkesky (2016) suggests that the homeland of Proto-Duho was in the Serranía de Chiribiquete.^[4]: 590

Jolkesky (2016) notes that there are lexical similarities with Chibchan languages due to contact, which may point to the earlier presence of Chibchan speakers in the Orinoco basin.^[4]: 325

Internal classification of the Duho language family by Jolkesky (2016):^[4]

Jolkesky's Duho languages have shared forms in *ʧ for "I", *kʷ for "you" and *t for "we", which are found in all languages.

language	I	thou	he	she	we	they
Ticuna	ʧò-	ku-	dĩ-	ɡĩ- /i-	tò-	ta-́
Yuri	tshuu	wikú	di	-	too	-
Saliba	ʧ-	ũku, kʷ-	Ø-, i-, -di	x-, -x	t-	h-
Piaroa	ʧ(u)-	(u)ku, kʷ-	Ø-, -de	hʷ-, -h	t(u)-	tʰ(a)-
Wirö	ʧ(V)-	ɯkʷɯ, kʷ(V)-	Ø-	h(V)-, -h	d(V)-, -dɯtʰɯ	tʰ(V)-
Hodi	ʰtæ	ʰkæ	dæ	-	ʰtai	hai
Betoi	r(u)-	uhu, h(u)-	Ø-, -ri	Ø-	r-, -nuto	?

Several basic words in Duho languages appear to be related. The following examples are given, with further parallels in Sape:

language	tree	mouth	head	hair	path	eat	spirit	offspring	breast	who	what
Ticuna	dãi	àː	èrú	ʧi	bã̀	ɡõ̀ː	ã́ẽ̀	dẽ́	biĩ́	tèẽ́	tàː
Yuri	noi	i à	gerühó	ii	-mó	-	-	o nné	-	-	-
Saliba	-	aha	iʤu	-	maa(-na)	ikua	õãĩ	nẽ(-ẽ)	omixe	ã-diha	ã-daha
Piaroa	dawi	æ	u(-ju)	-ʦˀe	mæ(-næ)	ku	ãẽ	ĩtʰĩ	ami	di	dæhe
Wirö	towi	a	u; -ʤu	-ˀʤe	ma(-na)	ku(-õ)	-	ĩtʰĩ	omu	ti	tahi
Hodi	ʰtawɯ	a	ʰtu	-	ma(-na); -ma	ʰku-õ	ãwẽ(-no)	ĩni	me(e)	-	-
(Sape)	tapa	itu	koyanukú, moynaku	pa	mu	ko/ku	-	katona	wi	pante	pemente