Faktor transfera

Faktori transfera su imunski molekuli koji izazivaju antigen-specifičan ćelijski-posredovani imunitet, prvenstveno odloženu hipersenzitivnost i produkciju limfokina, kao i vezivanje za same antigene. Oni imaju molekularnu težinu od aproksimativno 5000 Daltona. Oni su formirani od aminokiselina bez posttranskripcionih modifikacija.[1] Faktore transfera je otkrio Henri Šervud Lovrenc.[2]

Upotreba

Faktori transfera su bili promovisani kao tretman za rak, multiplu sklerozu, amiotrofnu lateralnu sklerozu, HIV, Alchajmerovu bolest, autizam, dijabetes, neplodnost, muskularnu slabost, genetske i infektivne bolesti, herpes, Epštajn-Barov virus, hepatitis, astma i sindrom hroničnog umora. Nema dokaza da su ovi molekuli efektivni za tretman većine od tih oboljenja.[3][4][5][6] Faktori transfera mogu da pomognu da se imunizuju deca sa leukemijom protiv herpes zoster[6] FDA reguliše faktore transfera kao dijetalne suplemente[3] i izdala je upozorenje da za ove supstance nije dokazano da su efektivne i bezbedne za tretman bilo kog oboljenja.[7]

Povezano

Reference

  1. Kirkpatrick CH (June 1993). „Structural nature and functions of transfer factors”. Ann. N. Y. Acad. Sci. 685: 362–8. PMID 8363241. 
  2. Al-Askari, S (2009). „Henry Sherwood Lawrence”. Biographical Memoirs, Volume 90. United States National Academy of Sciences. str. 237-255. ISBN 0309121485. 
  3. 3,0 3,1 „Transfer Factor”. Memorial Sloan–Kettering Cancer Center. 8. 10. 2009.. Arhivirano iz originala na datum 2010-06-26. Pristupljeno 16. 2. 2010. 
  4. Barrett, S (28. 3. 2007.). „Be Wary of Multiple Sclerosis "Cures"”. Quackwatch. Pristupljeno 12. 2. 2010. 
  5. Ernst E, Schmidt K, Baum M (2006). „Complementary/Alternative therapies for the treatment of breast cancer. A systematic review of randomized clinical trials and a critique of current terminology”. Breast J 12 (6): 526–30. DOI:10.1111/j.1524-4741.2006.00340.x. PMID 17238981. 
  6. 6,0 6,1 „Transfer Factor”. WebMD. Pristupljeno 16. 2. 2010. 
  7. Barrett, S (2. 6. 2005.). „Warning Letter”. Quackwatch. Arhivirano iz originala na datum 2010-10-26. Pristupljeno 12. 2. 2010. 

Literatura

  • Al-Askari, S (2009). „Henry Sherwood Lawrence”. Biographical Memoirs, Volume 90. United States National Academy of Sciences. str. 237-255. ISBN 0309121485. 

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