3-Metiltiofentanil

3-Metiltiofentanil
(IUPAC) ime
(RS)-N3-metil-1-[2-(2-tienil)etil]piperidin-4-ilN-fenilpropanamid
Klinički podaci
Identifikatori
CAS broj 86052-04-2
ATC kod nije dodeljen
PubChem[1][2] 62296
DrugBank DB01439
ChemSpider[3] 56092
ChEBI CHEBI:53763 DaY
Hemijski podaci
Formula C21H28N2OS 
Mol. masa 356,526 g/mol
SMILES eMolekuli & PubHem
Sinonimi N-[3-metil-1-(2-tiofen-2-iletil)-4-piperidil]-N-fenil-propanamid; 3-metil-tiofentanil
Farmakoinformacioni podaci
Trudnoća ?
Pravni status ? (CA) ? (UK) ? (SAD)

3-Metiltiofentanil je opioidni analgetik koji je analog fentanila.

3-Metiltiofentanil je bio tokom kraćeg perioda u prodaji na crno u Americi tokom 1980-tih, pre nego što je uveden zakon kojim se kontrolišu čitave familije lekova po osnovi njihove strukturne sličnosti.[4]

3-Metiltiofentanil ima slično dejstvo sa fentanilom. Nuspojave fentanilnih analoga su slične nuspojavama fentanila, i obuhvataju svrab, mučninu i potencijalno ozbiljnu respiratornu derpesiju koja može da dovede do smrtnog slučaja.

Reference

  1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. ↑ Henderson GL. Designer Drugs: Past History and Future Prospects. Journal of Forensic Sciences 1988; 33(2):569-575.

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