Acetilmorfon

Acetilmorfon
Klinički podaci
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 14696-22-1
ATC kod nije dodeljen
PubChem[1][2] 625177
ChemSpider[3] 21106250
Hemijski podaci
Formula C19H21NO4 
Mol. masa 327,374
SMILES eMolekuli & PubHem
Sinonimi Acetylmorphone, Dihydromorphinone acetate, 3-acetyl-7,8-dihydromorphin-6-one
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Acetilmorfon je organsko jedinjenje, koje sadrži 19 atoma ugljenika i ima molekulsku masu od 327,374 Da.

Osobine

Osobina Vrednost
Broj akceptora vodonika 5
Broj donora vodonika 0
Broj rotacionih veza 2
Particioni koeficijent[4] (ALogP) 1,7
Rastvorljivost[5] (logS, log(mol/L)) -2,8
Polarna površina[6] (PSA, Å2) 55,8

Reference

  1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. ↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o. 
  5. ↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573. 
  6. ↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286. 

Literatura

Vanjske veze

Portal Medicina
Portal Hemija

Read other articles:

Stade de Wembley

Cet article concerne le stade inauguré en 2007. Pour l'ancien stade, voir Stade de Wembley (1923). Pour le quartier, voir Wembley. Wembley StadiumUEFA GénéralitésSurnom The Venue of Legends, The Home of FootballAdresse Wembley Londres HA9 0WSConstruction et ouvertureDébut de construction 2004Ouverture 17 mars 2007[1]Architecte Foster + Partners HOK Sport Venue EventIngénieurs Mott MacDonald, SKM, Aurecon (toit), Cleveland Bridge & Engineering Company (en) (arc)Coût de construc...

 

Rainie Yang

Biografi ini tidak memiliki sumber tepercaya sehingga isinya tidak dapat dipastikan. Bantu memperbaiki artikel ini dengan menambahkan sumber tepercaya. Materi kontroversial atau trivial yang sumbernya tidak memadai atau tidak bisa dipercaya harus segera dihapus.Cari sumber: Rainie Yang – berita · surat kabar · buku · cendekiawan · JSTOR (Pelajari cara dan kapan saatnya untuk menghapus pesan templat ini) Ini adalah nama Tionghoa; marganya adalah Yang. R...

 

Rashomon

RashomonPoster Jepang untuk RashomonSutradaraAkira KurosawaProduserMinoru JingoSkenarioAkira Kurosawa,Shinobu HashimotoBerdasarkanCerpen:Ryunosuke AkutagawaPemeranToshiro Mifune,Masayuki Mori,Machiko Kyo,Takashi Shimura,Minoru ChiakiPenata musikFumio HayasakaSinematograferKazuo MiyagawaPenyuntingAkira KurosawaPerusahaanproduksiDaiei Film Co., Ltd.DistributorJepang:Daiei Film Co., Ltd.Amerika Serikat:RKO Radio PicturesTanggal rilisJepang:25 Agustus 1950Amerika Serikat:26 Desember 1951Dur...

1928 Utah gubernatorial election

For related races, see 1928 United States gubernatorial elections. 1928 Utah gubernatorial election ← 1924 November 6, 1928 1932 →   Nominee George Dern William Henry Wattis Party Democratic Republican Popular vote 102,953 72,306 Percentage 58.50% 41.08% County resultsDern:      50–60%      60–70%Wattis:      50–60%      60–70% Governor before election G...

 

العلاقات البوتانية الناوروية

العلاقات البوتانية الناوروية بوتان ناورو   بوتان   ناورو تعديل مصدري - تعديل   العلاقات البوتانية الناوروية هي العلاقات الثنائية التي تجمع بين بوتان وناورو.[1][2][3][4][5] مقارنة بين البلدين هذه مقارنة عامة ومرجعية للدولتين: وجه المقارنة بوتان ...

 

حركة حماس

حركة المقاومة الإسلاميةحماسالعلمالتأسيسالاسم الرسمي حركة المقاومة الإسلاميةالنوع حركة سياسية — حركة مقاومة - حركة تحريرالبلد  دولة فلسطين المقر الرئيسي غزة التأسيس 10 ديسمبر 1987[1] الشخصياتالمؤسسون أحمد ياسين[2]عبد العزيز الرنتيسيمحمود الزهار الرئيس يحيى السن...

Lempok

Artikel ini perlu dikembangkan agar dapat memenuhi kriteria sebagai entri Wikipedia.Bantulah untuk mengembangkan artikel ini. Jika tidak dikembangkan, artikel ini akan dihapus. Lempok durian asal Pulau Bangka Lempok, lempuk atau lempouk adalah jenis dodol yang dijumpai di kawasan Sumatra. Selain, lempok durian yang banyak dikenal, lempok juga dibuat dari nanas, kentang[1], cempedak[2] dan nangka. Lempok atau dodol kentang dapat ditemukan di Kabupaten Kerinci, Jambi.[1]...

 

Associazione Fascista Calcio Vicenza 1934-1935

Questa voce sull'argomento stagioni delle società calcistiche italiane è solo un abbozzo. Contribuisci a migliorarla secondo le convenzioni di Wikipedia. Segui i suggerimenti del progetto di riferimento. Voce principale: Vicenza Calcio. Associazione Fascista Calcio VicenzaStagione 1934-1935Sport calcio SquadraVicenza Calcio Allenatore József Viola Serie B11º posto nel girone B. Retrocessa in Serie C. Maggiori presenzeCampionato: Camolese, Cesaro (28) Miglior marcatoreCampionato: Cam...

 

Mark Lyall Grant

British diplomat (born 1956) SirMark Lyall GrantGCMGMark Lyall Grant speaking at Chatham House in 2011United Kingdom National Security AdviserIn office7 September 2015 – 13 April 2017Prime MinisterDavid Cameron Theresa MayPreceded byKim DarrochSucceeded byMark SedwillPermanent Representative of the United Kingdom to the United NationsIn office1 November 2009 – May 2015MonarchElizabeth IIPrime MinisterGordon Brown David CameronPreceded byJohn SawersSucceeded byMatthew Ryc...

Sopwith Cuckoo

Sopwith CuckooDescrizioneTipoaerosilurante Equipaggio1 Costruttore Sopwith Aviation Data primo vologiugno 1917 Data entrata in serviziosettembre 1918 Data ritiro dal servizio1923 Utilizzatore principale RAF Esemplari232 Dimensioni e pesiLunghezza8,68 m (28 ft 6 in) Apertura alare14,25 m (46 ft 9 in) Altezza3,25 m (10 ft 8 in) Superficie alare52,58 m² (566 ft²) Peso a vuoto997 kg (2 199 lb) Peso carico1 761 kg (3 883 lb) PropulsioneMotoreun Sunbeam Arab Potenza200 hp (149 kW) ...

 

Lee Bell

English footballer For other uses, see Lee Bell (disambiguation). Lee Bell Lee Bell in March 2023Personal informationFull name Lee Bell[1]Date of birth (1983-01-26) 26 January 1983 (age 41)[1]Place of birth Alsager, EnglandHeight 5 ft 10 in (1.78 m)[1]Position(s) MidfielderTeam informationCurrent team Crewe Alexandra (manager)Youth career1997–2002 Crewe AlexandraSenior career*Years Team Apps (Gls)2002–2007 Crewe Alexandra 53 (3)2003 → Shrewsbu...

 

Rick Rescorla

War hero, and victim and hero of 9/11 (1939–2001) Rick RescorlaBirth nameCyril Richard RescorlaBorn(1939-05-27)May 27, 1939[1]Hayle, Cornwall, United KingdomDiedSeptember 11, 2001(2001-09-11) (aged 62)South Tower, World Trade Center, New York CityCause of deathCollapse of 2 World Trade Center during the September 11 attacksAllegiance United States United KingdomService/branch United States Army British ArmyYears of service1963–1990 (U.S.)[2&#...

Harriman State Park (New York)

For the state park in Idaho, see Harriman State Park (Idaho). State park of New York state, United States Harriman State ParkView from Harriman State Park, facing northLocation of Harriman State Park in New York StateLocationOrange / Rockland counties, New York, United StatesCoordinates41°14′35″N 74°06′02″W / 41.24306°N 74.10056°W / 41.24306; -74.10056Area47,527 acres (192.33 km2)[1]Established1910Visitors1,425,000 (in 2014)[1]...

 

Elon Galusha

American attorney and clergyman From 1874's History of the Second Advent Message and Mission, Doctrine and People Part of a series on AdventismWilliam Miller BackgroundChristianityProtestantismAnabaptistsRestorationismPietismMillerism HistorySecond Great AwakeningGreat Disappointment BiographiesWilliam MillerNelson H. BarbourJoseph BatesSylvester BlissElon GalushaApollos HaleJoshua V. HimesJosiah LitchRachel O. PrestonT. M. PrebleGeorge StorrsJohn T. WalshJonas WendellEllen G. WhiteJames Whit...

 

Abdul Azis

Abdul Azis (lahir 5 Januari 1986) adalah mantan anggota Polri atau Kepolisian Republik Indonesia (Polri) dengan pangkat Aipda atau Ajun Inspektur Polisi Dua kelahiran Enrekang Abdul AzisM.H Bupati Kolaka TimurPetahanaMulai menjabat 27 November 2023(Pelaksana tugas: 24 Agustus 2022 – 27 November 2023)PresidenJoko WidodoGubernurAndap Budhi Revianto (penjabat)PendahuluAbdul AzisPenggantiPetahanaWakil Bupati Kolaka TimurMasa jabatan24 Agustus 2022 – 27 November 2023PresidenJoko W...

2020年夏季奧林匹克運動會義大利代表團

2020年夏季奥林匹克运动会意大利代表團意大利国旗IOC編碼ITANOC意大利國家奧林匹克委員會網站www.coni.it（英文）（意大利文）2020年夏季奥林匹克运动会（東京）2021年7月23日至8月8日（受2019冠状病毒病疫情影响推迟，但仍保留原定名称）運動員366參賽項目31个大项旗手开幕式：埃利亚·维维安尼（自行车）和杰西卡·罗西（射击）[1]閉幕式：馬塞爾·雅各布斯（田徑）[...

 

Knuth Prize

Prize given by ACM and IEEE for outstanding contributions to the foundations of computer science Gary Miller presents Volker Strassen with the 2008 Knuth Prize at SODA 2009 The Donald E. Knuth Prize is a prize for outstanding contributions to the foundations of computer science, named after the American computer scientist Donald E. Knuth. History The Knuth Prize has been awarded since 1996 and includes an award of US$5,000. The prize is awarded by ACM SIGACT and by IEEE Computer Society's Tec...

 

1291 en santé et médecine

Chronologies Données clés 1288 1289 1290  1291  1292 1293 1294Décennies :1260 1270 1280  1290  1300 1310 1320Siècles :XIe XIIe  XIIIe  XIVe XVeMillénaires :-Ier Ier  IIe  IIIe Chronologies thématiques Religion (,) et * Croisades   Science () et Santé et médecine   Terrorisme Calendriers Romain Chinois Grégorien Julien Hébraïque Hindou Hégirien Persan Républicain modifier Années de la santé et de la médecine ...

巴比伦大淫妇

本條目存在以下問題，請協助改善本條目或在討論頁針對議題發表看法。 此條目之中立性有争议。其內容、語調可能帶有明顯的個人觀點或地方色彩。 (2009年3月28日)加上此模板的編輯者需在討論頁說明此文中立性有爭議的原因，以便讓各編輯者討論和改善。在編輯之前請務必察看讨论页。 此條目過於依赖第一手来源。请補充第二手及第三手來源，以改善这篇条目。 此條目�...

 

Glossary of figure skating terms

List of definitions of terms and jargon used in figure skating The following is a glossary of figure skating terms, sorted alphabetically. Contents:  Top 0–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0–9 A 3 turn 3 turn Main article: 3 turn Also three turn. A one-foot turn with a change of edge that results in a '3' shape traced on the ice 4CC An abbreviation for the Four Continents Figure Skating Championships 6.0 system Main article: 6.0 system The old scoring system ...