Benzilmorfin

Benzilmorfin
Klinički podaci
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 14297-87-1
ATC kod nije dodeljen
PubChem[1][2] 5362507
DrugBank DB01573
ChemSpider[3] 4515062
Hemijski podaci
Formula C24H25NO3 
Mol. masa 375,460
SMILES eMolekuli & PubHem
Fizički podaci
Tačka topljenja 132 °C (270 °F)
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Benzilmorfin je organsko jedinjenje, koje sadrži 24 atoma ugljenika i ima molekulsku masu od 375,460 Da.[4][5]

Osobine

Osobina Vrednost
Broj akceptora vodonika 4
Broj donora vodonika 1
Broj rotacionih veza 3
Particioni koeficijent[6] (ALogP) 3,2
Rastvorljivost[7] (logS, log(mol/L)) -4,8
Polarna površina[8] (PSA, Å2) 41,9

Reference

  1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. DOI:10.1093/nar/gkq1126. PMC 3013709. PMID 21059682. 
  5. ↑ David S. Wishart, Craig Knox, An Chi Guo, Dean Cheng, Savita Shrivastava, Dan Tzur, Bijaya Gautam, and Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research 36 (Database issue): D901-6. DOI:10.1093/nar/gkm958. PMC 2238889. PMID 18048412. 
  6. ↑ Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o. Arhivirano iz originala na datum 2014-07-22. Pristupljeno 2014-04-05. 
  7. ↑ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573. 
  8. ↑ Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286. 

Literatura

Vanjske veze

Portal Medicina
Portal Hemija

Read other articles:

Bahasa Cherokee

Cari artikel bahasa  Cari berdasarkan kode ISO 639 (Uji coba)  Kolom pencarian ini hanya didukung oleh beberapa antarmuka Halaman bahasa acak Bahasa Cherokee ᏣᎳᎩ Tsalagi Dituturkan diAmerika SerikatWilayahOklahoma Timur; Great Smoky Mountains[1] dan Qualla Boundary di Karolina Utara[2] Also in Arkansas.[3]Penutur15.000 hingga 22.000 Rincian data penutur Jumlah penutur beserta (jika ada) metode pengambilan, jenis, tanggal, dan tempat.[4] 12....

 

Dedé

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada November 2022. DedéInformasi pribadiNama lengkap Anderson Vital da SilvaTanggal lahir 1 Juli 1988 (umur 35)Tempat lahir Volta Redonda, BrasilTinggi 1,92 m (6 ft 3+1⁄2 in)Posisi bermain Bek tengah, SweeperInformasi klubKlub saat ini Cruzeir...

 

Élections législatives françaises de 1799

1798 mai 1815 Élections législatives françaises de 1799 500 députés 9 et 16 avril 1799 Type d’élection Élections législatives Corps électoral et résultats Votants ? Montagnards – Jean Antoine Debry Voix ? 48,00 %  Députés élus 240  134 Clichyens – François Barthélemy Voix ? 30,00 %  Députés élus 150 Ultraroyalistes – Jean-Claude Fabre de l'Aude Voix ? 16,00 %  Députés élus 80 Extrêm...

Vancouver Hospital and Health Sciences Centre

Vancouver Hospital redirects here. For VHHSC's largest hospital, see Vancouver General Hospital. Hospital in British Columbia, CanadaVancouver Hospital and Health Sciences CentreVancouver Coastal HealthUBC Hospital as seen from Wesbrook MallGeographyLocationVancouver, British Columbia, CanadaCoordinates49°15′40″N 123°07′28″W / 49.26111°N 123.12444°W / 49.26111; -123.12444 (Vancouver Hospital and Health Sciences Centre)OrganizationCare systemPublic M...

 

Design management

Field of inquiry in business Design management is the business side of design. Design managers need to speak the language of the business and the language of design. Design management is a field of inquiry that uses design, strategy, project management and supply chain techniques to control a creative process, support a culture of creativity, and build a structure and organization for design. The objective of design management is to develop and maintain an efficient business environment in wh...

 

Katrina McClain

Questa voce sull'argomento cestisti statunitensi è solo un abbozzo. Contribuisci a migliorarla secondo le convenzioni di Wikipedia. Segui i suggerimenti del progetto di riferimento. Katrina McClain Katrina McClain (in maglia rossa) in azione alle Final-Four del 1985 Nazionalità  Stati Uniti Altezza 188 cm Peso 95 kg Pallacanestro Ruolo A Termine carriera 1998 Hall of fame Naismith Hall of Fame (2012)FIBA Hall of Fame (2023)Women's Basketball Hall of Fame (2006) Car...

Economy of Northern Ireland

This article has multiple issues. Please help improve it or discuss these issues on the talk page. (Learn how and when to remove these template messages) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Economy of Northern Ireland – news · newspapers · books · scholar · JSTOR (April 2021) (Learn how and when...

 

Ciołek coat of arms

Polish coat of arms CiołekBattle cryBiała, CiołekAlternative name(s)Biała, Taurus, Thaurus, VitulusEarliest mention1279 (seal), 1401 (record)Families185 names A Aksamitowski. B Bielański, Bielawski, Bieliński, Borkowski, Brzeski, Bzicki. C Cetys, Chabdziński, Chądzeński, Chądzyński, Chebdziński, Chędziński, Chodźko, Chudzewski, Cichoborski, Cielątko, Ciołek, Ciołkiewicz, Ciołkowicz, Ciszkiewicz, Czarnołoski, Czarnołuski, Czuszułowicz. D Dobroniecki, Dobrynicki, Dobryniec...

 

Hans Eklind

Swedish politician (born 1966) Hans EklindMember of the RiksdagIncumbentAssumed office 24 September 2018ConstituencyÖrebro County Personal detailsBorn1966 (age 57–58)Political partyChristian Democrats Hans Eklind (born 1966)[1] is a Swedish politician. Since September 2018,[update] he serves as Member of the Riksdag from the Christian Democrats representing the constituency of Örebro County.[2] He was also elected as Member of the Riksdag in Septe...

Museum of Pop Culture

Pour les articles homonymes, voir EMP. Experience Music ProjectScience Fiction MuseumInformations généralesOuverture 2000Site web www.mopop.orgCollectionsCollections Rock 'n' roll, Jimi Hendrix, science-fiction ...Nombre d'objets 80 000BâtimentArchitecte Frank GehryLocalisationPays États-UnisCommune SeattleAdresse Seattle Center325 5e avenue North, SeattleCoordonnées 47° 37′ 17″ N, 122° 20′ 53″ Omodifier - modifier le code - modifier Wik...

 

2015 Michigan Wolverines football team

American college football season 2015 Michigan Wolverines footballCitrus Bowl championCitrus Bowl, W 41–7 vs. FloridaConferenceBig Ten ConferenceDivisionEast DivisionRankingCoachesNo. 11APNo. 12Record10–3 (6–2 Big Ten)Head coachJim Harbaugh (1st season)Offensive coordinatorTim Drevno (1st season)Offensive schemePro-styleDefensive coordinatorD. J. Durkin (1st year), Greg Mattison (bowl game)Base defense4–3MVPJehu ChessonCaptains Joe Bolden (Senior yea...

 

Gorbals

Area in the city of Glasgow, Scotland Human settlement in ScotlandGorbalsScottish Gaelic: Gort a' bhaileGorbalsLocation within GlasgowArea0.83 km2 (0.32 sq mi) [1]Population6,030 (2015)[2]• Density7,265/km2 (18,820/sq mi)OS grid referenceNS 59100 64000Council areaGlasgow City CouncilLieutenancy areaGlasgowCountryScotlandSovereign stateUnited KingdomPost townGLASGOWPostcode districtG5Dialling code0141Police...

Clare McMeniman

Australia international netball player Clare McMeniman Personal informationFull name Clare Ferguson (née McMeniman)Born (1985-07-11) 11 July 1985 (age 38)Height 185 cm (6 ft 1 in)School Warwick West State SchoolJohn Paul CollegeUniversity University of QueenslandRelatives Hugh McMeniman (brother)Netball career Playing position(s): GD, WDYears Club team(s) Apps2004–2006 AIS Canberra Darters 2007–2016 Queensland Firebirds Years National team(s) Caps2014–2016 Aust...

 

WGBH (FM)

Public radio station in Boston For the television station, see WGBH-TV. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: WGBH FM – news · newspapers · books · scholar · JSTOR (December 2022) (Learn how and when to remove this message) WGBHBoston, MassachusettsUnited StatesBroadcast areaGreater BostonFreq...

 

First Football

Ada usul agar artikel ini digabungkan ke First Media (telekomunikasi). (Diskusikan) Diusulkan sejak April 2024. First FootballDiluncurkan2014 (sebagai BeritaSatu Sports)2017 (sebagai First Football)PemilikBeritaSatu Media Holdings (2014-2017)LinkNet (2014-sekarang)Negara IndonesiaBahasaBahasa IndonesiaSaluran seindukJakarta Globe News ChannelSitus webwww.beritasatu.com First Football (sebelumnya bernama BeritaSatu Sports) adalah saluran televisi olahraga yang mengudara sejak tahun 2014. Salur...

Chiri Chiri

Chiri ChiriAlbum studio karya MomolandDirilis4 September 2019 (2019-09-04)Direkam2018–2019GenreJ-popBahasaJepangLabelKingKronologi Momoland Momoland The Best ~Korean Ver.~(2018) Chiri Chiri(2019) Singel dalam album Chiri Chiri Bboom BboomDirilis: 13 Juni 2018 BaamDirilis: 7 November 2018 I'm So HotDirilis: 8 Mei 2019 Pinky LoveDirilis: 4 September 2019 Chiri Chiri adalah album studio debut berbahasa Jepang dari grup vokal wanita asal Korea Selatan Momoland. Album ini dirilis oleh K...

 

Giorgi Margvelashvili

Georgian politician For the chess player, see Giorgi Margvelashvili (chess player). Giorgi Margvelashviliგიორგი მარგველაშვილიMargvelashvili in 20184th President of GeorgiaIn office17 November 2013 – 16 December 2018Prime MinisterBidzina IvanishviliIrakli GaribashviliGiorgi KvirikashviliMamuka BakhtadzePreceded byMikheil SaakashviliSucceeded bySalome ZourabichviliFirst Deputy Prime Minister of GeorgiaIn office23 January 2013 – 18 July...

 

ميناء أشدود

ميناء أشدود ميناء أشدود (إسدود). المكان البلد إسرائيل المكان أشدود الإحداثيات 31°49′26.03″N 34°38′49.57″E / 31.8238972°N 34.6471028°E / 31.8238972; 34.6471028 التفاصيل دخول الخدمة 1965 المشغل سلطة موانئ إسرائيل المالك مجلس وزراء إسرائيل النوع Artificial مرافيء السفن 12 الإحصائيات حمولة سفن الشح�...

University of Kentucky

Public university in Lexington, Kentucky, US University of KentuckyLatin: Universitas KentuckiensisFormer namesAgricultural and Mechanical College of Kentucky (1865–1908)State University, Lexington, Kentucky (1908–1915)State University of Kentucky (1915–1922)MottoUnited We Stand, Divided We FallTypePublic land-grant research universityEstablishedFebruary 22, 1865; 159 years ago (February 22, 1865)AccreditationSACSAcademic affiliationsORAUURASpace-grantEndowment$2.13 billion...

 

Tempesta

Disambiguazione – Se stai cercando altri significati, vedi Tempesta (disambigua). Nubi associate a un forte temporale sopra Enschede, Paesi Bassi Una tempesta è un qualunque stato violento dell'atmosfera di un corpo celeste, che colpisce la sua superficie apportando condizioni meteorologiche severe. Può essere caratterizzato da vento forte, tuoni e fulmini (un temporale), precipitazioni intense, anche di ghiaccio (tempesta di ghiaccio), o da vento che trasporta alcune sostanze attraverso...