Izometadon

Izometadon
Klinički podaci
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 466-40-0
ATC kod nije dodeljen
PubChem[1][2] 10072
ChemSpider[3] 9675
Hemijski podaci
Formula C21H27NO 
Mol. masa 309,445
SMILES eMolekuli & PubHem
Sinonimi WIN-1783, BW 47-442
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

Izometadon je organsko jedinjenje, koje sadrži 21 atom ugljenika i ima molekulsku masu od 309,445 Da.

Osobine

Osobina Vrednost
Broj akceptora vodonika 2
Broj donora vodonika 0
Broj rotacionih veza 7
Particioni koeficijent[4] (ALogP) 4,4
Rastvorljivost[5] (logS, log(mol/L)) -5,7
Polarna površina[6] (PSA, Å2) 20,3

Reference

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A 102: 3762-3772. DOI:10.1021/jp980230o. 
  5. Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488-1493. DOI:10.1021/ci000392t. PMID 11749573. 
  6. Ertl P., Rohde B., Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714-3717. DOI:10.1021/jm000942e. PMID 11020286. 

Literatura

Vanjske veze

Read other articles:

A Love to KillPoster promosi untuk A Love to KillGenreMelodrama RomansaDitulis olehLee Kyung-heeSutradaraKim Kyu-taePemeranRainShin Min-ahKim Sa-rangLee Ki-wooPenggubah lagu temaChoi Sung-kwonNegara asalKorea SelatanBahasa asliKoreaJmlh. episode16ProduksiProduserJung Sung-hyoDurasi60 menit pada hari Senin dan Selasa pukul 21:55Rilis asliRilis31 Oktober (2005-10-31) –20 Desember 2005 (2005-12-20) Nama KoreaHangul이 죽일 놈의 사랑 Alih AksaraI juk-il nom-ui sarangMcCune...

 

العلاقات اليابانية الإريترية اليابان إريتريا   اليابان   إريتريا تعديل مصدري - تعديل   العلاقات اليابانية الإريترية هي العلاقات الثنائية التي تجمع بين اليابان وإريتريا.[1][2][3][4][5] مقارنة بين البلدين هذه مقارنة عامة ومرجعية للدولتين: وجه ال...

 

State highway IA-100 redirects here. For the Argentinian training aircraft currently under development, see FAdeA IA 100. Iowa Highway 100Iowa 100 highlighted in redRoute informationMaintained by Iowa DOTLength16.140 mi[1] (25.975 km)Major junctionsWest end US 30 / US 218 near Cedar RapidsMajor intersections I-380 / Iowa 27 in Cedar Rapids US 151 Bus. in Cedar Rapids East end US 151 / Iowa 13 in Marion LocationCount...

Men's Greco-Roman 60 kgat the Games of the XXXII OlympiadVenueMakuhari MesseDate1–2 August 2021Competitors16 from 16 nationsMedalists Luis Orta  Cuba Kenichiro Fumita  Japan Walihan Sailike  China Sergey Emelin  ROC← 20162024 → Wrestling at the2020 Summer OlympicsQualificationList of wrestlersFreestyleGreco-RomanWomen57 kg60 kg50 kg65 kg67 kg53 kg74 kg77 kg57 kg86 kg87 kg62 kg97 kg97 kg68 kg125 kg130 kg76 kgvte Main article: Wrestling at t...

 

Pertandingan Grup C Piala Dunia FIFA 2018 berlangsung pada tanggal 16 hingga 26 Juni 2018.[1] Grup ini terdiri dari Prancis, Australia, Peru, dan Denmark. Dua tim peringkat teratas lolos ke babak 16 besar.[2] Tim peserta Posisi undian Tim Pot Konfederasi Metodekualifikasi Tanggallolos Penampilan diputaran final Penampilanterakhir Penampilanterbaik Peringkat FIFA Oktober 2017[cat. 1] Juni 2018 C1  Prancis 1 UEFA Juara Grup A Zona Eropa 10 Oktober 2017 Ke-15 2014 (p...

 

Vladimir city of federal subject significance of Russiakota besarkota Владимир (ru) flag of Vladimir Q16636294 Tempat Negara berdaulatRusiaOblast di RusiaOblast VladimirUrban okrug in RussiaMunicipal Formation of the City of Vladimir Ibu kota dariOblast Vladimir (1944–)Vladimir Province (1719–1775 (Kalender Masehi Julius))Municipal Formation of the City of Vladimir (2004–)Vladimir Viceroyalty (1778 (Kalender Masehi Julius)–1796 (Kalender Masehi Julius))Vladimir...

This article is about the film named My People, My Country. For the eponymous song, see My People, My Country (song). 2019 Chinese filmMy People, My CountryChinese nameTraditional Chinese我和我的祖國Simplified Chinese我和我的祖国Literal meaningme and my motherlandTranscriptionsStandard MandarinHanyu Pinyinwǒ hé wǒ de zǔguó Directed byChen KaigeZhang YibaiGuan HuXue XiaoluXu ZhengNing HaoWen MuyeProduced byHuang JianxinStarringHuang BoGeng LeOho OuZhang YiRen SuxiWu JingM...

 

Species of mammal Bates’s pygmy antelope Conservation status Least Concern  (IUCN 3.1)[1] Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Class: Mammalia Order: Artiodactyla Family: Bovidae Genus: Nesotragus Species: N. batesi Binomial name Nesotragus batesi(De Winton, 1903) range Synonyms[1] Neotragus batesi Bates's pygmy antelope (Nesotragus batesi), also known as the dwarf antelope, pygmy antelope[2] or Bates' dwarf antelop...

 

This article may need to be rewritten to comply with Wikipedia's quality standards. You can help. The talk page may contain suggestions. (May 2009) This is a list of fighter aces in World War II, ordered by national origin. See also List of World War II flying aces. Australia There were 103 air aces from Australia during the Second World War. For more information, see List of World War II aces from Australia. Austria There were 51 air aces from Austria during the Second World War. For more i...

Hungarian-Austrian composer and pianist (1936–2019) The native form of this personal name is Erőd Iván. This article uses Western name order when mentioning individuals. Iván Erődin June 2011BornErőd Iván(1936-01-02)2 January 1936Budapest, HungaryDied24 June 2019(2019-06-24) (aged 83)Vienna, AustriaEducationFranz Liszt Academy of MusicOccupations Composer Pianist Academic teacher Organizations Franz Liszt Academy of Music University of Music and Performing Arts Graz Awards Fe...

 

Cet article est une ébauche concernant une compétition de football et l’Albanie. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Coupe d'Albanie Logo de la Coupe d'Albanie de footballGénéralités Sport Football Création 1939 Organisateur(s) Fédération albanaise de football Éditions 69 (en 2020-2021) Périodicité Annuelle Nations Albanie Palmarès Tenant du titre KF Egnatia Rrogozhinë Plus titré(s) K...

 

Historic commercial building in Queens, New York United States historic placeJ. Kurtz and Sons Store BuildingU.S. National Register of Historic PlacesNew York City Landmark No. 1132 Seen on a snowy March day in 2017Show map of New York CityShow map of New YorkShow map of the United StatesLocation162-24 Jamaica Ave., Queens, New YorkCoordinates40°42′15.6″N 73°47′49″W / 40.704333°N 73.79694°W / 40.704333; -73.79694Arealess than one acreBuilt1931Arch...

この記事はenから大ざっぱに翻訳されたものであり、場合によっては不慣れな翻訳者や機械翻訳によって翻訳されたものかもしれません。翻訳を改善してくださる方を募集しています。 フェミニズム 種類(英語版) 原理主義 アナキスト(英語版) 無神論(英語版) ブラック(英語版) チカーナ(英語版) キリスト教(英語版) 保守(英語版) カルチュラル サイバ�...

 

Valenciennescomune Valenciennes – Veduta LocalizzazioneStato Francia RegioneAlta Francia Dipartimento Nord ArrondissementValenciennes CantoneValenciennes TerritorioCoordinate50°21′N 3°32′E50°21′N, 3°32′E (Valenciennes) Altitudine42 m s.l.m. Superficie13,84 km² Abitanti43 229[1] (2019) Densità3 123,48 ab./km² Altre informazioniCod. postale59300 Fuso orarioUTC+1 Codice INSEE59606 CartografiaValenciennes Sito istituzionaleModifica dati...

 

Cet article est une ébauche concernant le rugby à XV et la Yougoslavie. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Yougoslavie Premier match officiel31 juillet 1968 Roumanie 11 – 3 Yougoslavie Plus large victoire15 mai 1982 Yougoslavie 46 – 6 Danemark Plus large défaite20 septembre 1979 France 86 – 6 Yougoslavie Données clés Coupe du monde   · Participations aucune · Meilleur ré...

Opera by Max Bruch Hermione is an opera in 4 acts, Op. 40, by Max Bruch to a libretto by Emil Hopffer, based on Shakespeare's The Winter's Tale. The opera premiered March 21, 1872, in Berlin.[1] Recordings Aria of Leontes (No. 7): Setzt Ihnen nach!, Aria of Leontes (No. 19): Allein, allein mit meinem Gram by Franz Hawlata [de] bass, Capriccio 1996 References ^ Operas in German: A Dictionary, Margaret Ross Griffel, 1990, p. 304: Hermione, opera in four acts by Max Bruch; l...

 

1992 television film directed by Paul Seed Dead Ahead: The Exxon Valdez DisasterGenreDramaWritten byMichael BakerDirected byPaul SeedStarringChristopher LloydJohn HeardRip TornBob GuntonMichael MurphyMark MetcalfMusic byDavid FergusonCountry of originUnited StatesOriginal languageEnglishProductionExecutive producersRichard BrokeColin CallenderLeslie WoodheadProducersJohn SmithsonDavid M. ThompsonProduction locationsAlaskaVancouverCinematographyIan PunterEditorDave KingRunning time90 minutesPr...

 

This is a list of members of the Western Australian Legislative Council from October 1870 to June 1872. The chamber had 18 members, as specified by the Legislative Council Act 1870 (33 Vict, No. 13). Section 1 of this Act specified that a minimum of one-third of the Council would be appointed by the Crown. Three of these were official nominees who were part of the Continuous Ministry—namely the Colonial Secretary, Attorney-General and the Surveyor-General—while the remaining three were n...

Алекс Фергюсон — 27-кратный обладатель награды Тренер месяца английской Премьер-лиги (англ. Manager of the Month award) — награда лучшему тренеру Премьер-лиги, вручаемая по итогам каждого месяца в течение игрового сезона. Победитель предыдущего месяца определяется в первую ...

 

Not to be confused with Animism. You can help expand this article with text translated from the corresponding article in Japanese. (July 2019) Click [show] for important translation instructions. View a machine-translated version of the Japanese article. Machine translation, like DeepL or Google Translate, is a useful starting point for translations, but translators must revise errors as necessary and confirm that the translation is accurate, rather than simply copy-pasting machine-trans...