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RPL4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UG0, 4V6X, 5AJ0, 4UJD, 5A8L, 4D67, 4D5Y, 4UJE, 4UJC
Identifiers
Aliases	RPL4, L4, Ribosomal protein L4
External IDs	OMIM: 180479; MGI: 1915141; HomoloGene: 748; GeneCards: RPL4; OMA:RPL4 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	66,524,532 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	64,085,948 bp
RNA expression pattern
	Top expressed in
	embryo; ; ganglionic eminence; ; cartilage tissue; ; ventricular zone; ; vulva; ; tail of epididymis; ; glutes; ; smooth muscle tissue; ; superficial temporal artery; ; caput epididymis;
	Top expressed in
	tail of embryo; ; genital tubercle; ; epiblast; ; ovary; ; blastocyst; ; ventricular zone; ; ganglionic eminence; ; uterus; ; embryo; ; urinary bladder;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; structural constituent of ribosome; RNA binding;
Cellular component	cytoplasm; cytosol; ribosome; membrane; focal adhesion; nucleolus; cytosolic large ribosomal subunit; extracellular exosome; nucleus; rough endoplasmic reticulum; ribonucleoprotein complex;
Biological process	protein biosynthesis; viral transcription; SRP-dependent cotranslational protein targeting to membrane; translational initiation; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; rRNA processing; cytoplasmic translation;
	Sources:Amigo / QuickGO
Orthologs
	6124
	67891
	ENSG00000174444
	ENSMUSG00000032399
	P36578
	Q9D8E6
	NM_000968
	NM_024212
	NP_000959
	NP_077174
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene.^[5]^[6]^[7]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L4E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000174444 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032399 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
^ Bagni C, Mariottini P, Annesi F, Amaldi F (Feb 1994). "Human ribosomal protein L4: cloning and sequencing of the cDNA and primary structure of the protein". Biochim Biophys Acta. 1216 (3): 475–8. doi:10.1016/0167-4781(93)90017-8. PMID 8268230.
^ ^a ^b "Entrez Gene: RPL4 ribosomal protein L4".

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