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EIF3H
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J8B, 3J8C
Identifiers
Aliases	EIF3H, EIF3S3, eIF3-gamma, eIF3-p40, eukaryotic translation initiation factor 3 subunit H
External IDs	OMIM: 603912; MGI: 1915385; HomoloGene: 2785; GeneCards: EIF3H; OMA:EIF3H - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	116,766,925 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	51,728,919 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; gonad; ; left ovary; ; parotid gland; ; monocyte; ; right ovary; ; body of uterus; ; canal of the cervix; ; lymph node; ; ectocervix;
	Top expressed in
	neural layer of retina; ; yolk sac; ; ventricular zone; ; tail of embryo; ; genital tubercle; ; lip; ; morula; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; muscle of thigh;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; translation initiation factor activity; RNA binding; metallopeptidase activity;
Cellular component	cytoplasm; cytosol; eukaryotic translation initiation factor 3 complex; eukaryotic translation initiation factor 3 complex, eIF3m; extracellular exosome; membrane; eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; polysomal ribosome;
Biological process	translational initiation; regulation of translational initiation; protein biosynthesis; formation of cytoplasmic translation initiation complex; cytoplasmic translational initiation; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	8667
	68135
	ENSG00000147677
	ENSMUSG00000022312
	O15372
	Q91WK2
	NM_003756
	NM_080635
	NP_003747
	NP_542366
	Wikidata
View/Edit Human	View/Edit Mouse

Eukaryotic translation initiation factor 3 subunit H (eIF3h) is a protein that in humans is encoded by the EIF3H gene.^[5]^[6]

Interactions

eIF3h has been shown to interact with eIF3a.^[7]^[8]^[9]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000147677 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022312 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Asano K, Vornlocher HP, Richter-Cook NJ, Merrick WC, Hinnebusch AG, Hershey JW (Nov 1997). "Structure of cDNAs encoding human eukaryotic initiation factor 3 subunits. Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042–52. doi:10.1074/jbc.272.43.27042. PMID 9341143.
^ "Entrez Gene: EIF3S3 eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa".
^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
^ Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J. Biol. Chem. 273 (48): 31901–8. doi:10.1074/jbc.273.48.31901. PMID 9822659.

External links

Overview of all the structural information available in the PDB for UniProt: O15372 (Eukaryotic translation initiation factor 3 subunit H) at the PDBe-KB.