40S ribosomal protein S7 is a protein that in humans is encoded by the RPS7gene.[5][6][7]
In eukaryotes, ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[7]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Annilo T, Laan M, Stahl J, Metspalu A (Jan 1996). "The human ribosomal protein S7-encoding gene: isolation, structure and localization in 2p25". Gene. 165 (2): 297–302. doi:10.1016/0378-1119(95)00576-R. PMID8522193.
Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID8722009.
Mundus DA, Bulygin KN, Yamkovoy VI, et al. (1993). "Structural arrangement of the codon-anticodon interaction area in human placenta ribosomes. Affinity labelling of the 40S subunits by derivatives of oligoribonucleotides containing the AUG codon". Biochim. Biophys. Acta. 1173 (3): 273–82. doi:10.1016/0167-4781(93)90124-v. PMID8318536.
Chen D, Zhang Z, Li M, et al. (2007). "Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function". Oncogene. 26 (35): 5029–37. doi:10.1038/sj.onc.1210327. PMID17310983. S2CID9239498.
External links
Overview of all the structural information available in the PDB for UniProt: P62081 (40S ribosomal protein S7) at the PDBe-KB.