11213
73914
ENSG00000090376
ENSMUSG00000020227
Q9Y616
Q8K4B2
NM_007199NM_001142523
NM_028679NM_001359184
NP_001135995NP_009130
NP_082955NP_001346113
Interleukin-1 receptor-associated kinase 3 is an enzyme that in humans is encoded by the IRAK3 gene.[5][6] Using in vivo liposome-mediated delivery of CRISPR/Cas9 plasmid expressing IRAK3 gRNA, IRAK3 was shown to be responsible for endotoxin-induced expression of A20 and VE-cadherin in endothelial cells. Thus, IRAK3 is crucial for maintenance and repair of endothelial barrier after endotoxin-induced lung injury.[7]
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