List of EC numbers (EC 5)

This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee.^[1] The database is developed and maintained by Andrew McDonald.^[2]

EC 5.1: Epimerases and racemases

EC 5.1.1: Acting on Amino acids and Derivatives

EC 5.1.1.1: alanine racemase
EC 5.1.1.2: methionine racemase
EC 5.1.1.3: glutamate racemase
EC 5.1.1.4: proline racemase
EC 5.1.1.5: lysine racemase
EC 5.1.1.6: threonine racemase
EC 5.1.1.7: diaminopimelate epimerase
EC 5.1.1.8: 4-hydroxyproline epimerase
EC 5.1.1.9: arginine racemase
EC 5.1.1.10: amino-acid racemase
EC 5.1.1.11: phenylalanine racemase (ATP-hydrolysing)
EC 5.1.1.12: ornithine racemase
EC 5.1.1.13: aspartate racemase
EC 5.1.1.14: nocardicin-A epimerase
EC 5.1.1.15: 2-aminohexano-6-lactam racemase
EC 5.1.1.16: protein-serine epimerase
EC 5.1.1.17: isopenicillin-N epimerase
EC 5.1.1.18: serine racemase
EC 5.1.1.20: L-Ala-D/L-Glu epimerase *
EC 5.1.1.21: isoleucine 2-epimerase *
EC 5.1.1.22: 4-hydroxyproline betaine 2-epimerase *
EC 5.1.1.23: UDP-N-acetyl-α-D-muramoyl-L-alanyl-L-glutamate epimerase *
EC 5.1.1.24: histidine racemase *

*No Wikipedia article

EC 5.1.2: Acting on Hydroxy acids and Derivatives

EC 5.1.2.1: lactate racemase
EC 5.1.2.2: mandelate racemase
EC 5.1.2.3: 3-hydroxybutyryl-CoA epimerase
EC 5.1.2.4: acetoin racemase
EC 5.1.2.5: tartrate epimerase
EC 5.1.2.6: isocitrate epimerase
EC 5.1.2.7: tagaturonate epimerase *

*No Wikipedia article

EC 5.1.3: Acting on Carbohydrates and Derivatives

EC 5.1.3.1: ribulose-phosphate 3-epimerase
EC 5.1.3.2: UDP-glucose 4-epimerase
EC 5.1.3.3: aldose 1-epimerase
EC 5.1.3.4: L-ribulose-5-phosphate 4-epimerase
EC 5.1.3.5: UDP-arabinose 4-epimerase
EC 5.1.3.6: UDP-glucuronate 4-epimerase
EC 5.1.3.7: UDP-N-acetylglucosamine 4-epimerase
EC 5.1.3.8: N-acylglucosamine 2-epimerase
EC 5.1.3.9: N-acylglucosamine-6-phosphate 2-epimerase
EC 5.1.3.10: CDP-paratose 2-epimerase
EC 5.1.3.11: cellobiose epimerase
EC 5.1.3.12: The enzyme has never been purified and the activity was later shown not to exist
EC 5.1.3.13: dTDP-4-dehydrorhamnose 3,5-epimerase
EC 5.1.3.14: UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing)
EC 5.1.3.15: glucose-6-phosphate 1-epimerase
EC 5.1.3.16: UDP-glucosamine 4-epimerase
EC 5.1.3.17: heparosan-N-sulfate-glucuronate 5-epimerase
EC 5.1.3.18: GDP-mannose 3,5-epimerase
EC 5.1.3.19: chondroitin-glucuronate 5-epimerase
EC 5.1.3.20: ADP-glyceromanno-heptose 6-epimeras
EC 5.1.3.21: maltose epimerase
EC 5.1.3.22: L-ribulose-5-phosphate 3-epimerase
EC 5.1.3.23: UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
EC 5.1.3.24: N-acetylneuraminate epimerase
EC 5.1.3.25: dTDP-L-rhamnose 4-epimerase
EC 5.1.3.26: N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase *
EC 5.1.3.27: dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase *
EC 5.1.3.28: UDP-N-acetyl-L-fucosamine synthase *
EC 5.1.3.29: L-fucose mutarotase *
EC 5.1.3.30: D-psicose 3-epimerase *
EC 5.1.3.31: D-tagatose 3-epimerase *
EC 5.1.3.32: L-rhamnose mutarotase *
EC 5.1.3.33: 2-epi-5-epi-valiolone epimerase *
EC 5.1.3.34: monoglucosyldiacylglycerol epimerase *
EC 5.1.3.35: 2-epi-5-epi-valiolone 7-phosphate 2-epimerase *
EC 5.1.3.36: heparosan-glucuronate 5-epimerase *
EC 5.1.3.37: mannuronan 5-epimerase *
EC 5.1.3.38: D-erythrulose 1-phosphate 3-epimerase *
EC 5.1.3.39: L-erythrulose 4-phosphate epimerase. The activity has been shown not to take place. *
EC 5.1.3.40: D-tagatose 6-phosphate 4-epimerase *
EC 5.1.3.41: fructoselysine 3-epimerase *
EC 5.1.3.42: D-glucosamine-6-phosphate 4-epimerase *
EC 5.1.3.43: sulfoquinovose mutarotase *
EC 5.1.3.44: mannose 2-epimerase *

*No Wikipedia article

EC 5.1.99: Acting on Other Compounds

EC 5.1.99.1: methylmalonyl-CoA epimerase
EC 5.1.99.2: 16-hydroxysteroid epimerase
EC 5.1.99.3: allantoin racemase
EC 5.1.99.4: α-methylacyl-CoA racemase
EC 5.1.99.5: hydantoin racemase
EC 5.1.99.6: NAD(P)H-hydrate epimerase
EC 5.1.99.7: dihydroneopterin triphosphate 2′-epimerase *
EC 5.1.99.8: 7,8-dihydroneopterin epimerase *

*No Wikipedia article

EC 5.2: cis-trans-Isomerases

EC 5.2.1: cis-trans Isomerases (only sub-subclass identified to date)

EC 5.2.1.1: maleate isomerase
EC 5.2.1.2: maleylacetoacetate isomerase
EC 5.2.1.3: Now known to be catalysed by a pathway involving EC 1.1.1.300, NADP-retinol dehydrogenase; EC 2.3.1.135, phosphatidylcholine—retinol O-acyltransferase; EC 3.1.1.64, retinoid isomerohydrolase; and EC 1.1.1.315, 11-cis-retinol dehydrogenase.
EC 5.2.1.4: maleylpyruvate isomerase
EC 5.2.1.5: linoleate isomerase
EC 5.2.1.6: furylfuramide isomerase
EC 5.2.1.7: transferred to EC 3.1.1.64, retinoid isomerohydrolase
EC 5.2.1.8: peptidylprolyl isomerase
EC 5.2.1.9: farnesol 2-isomerase
EC 5.2.1.10: 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
EC 5.2.1.11: The existence of this enzyme has been called into question by one of the authors of the reference cited
EC 5.2.1.12: ζ-carotene isomerase
EC 5.2.1.13: prolycopene isomerase
EC 5.2.1.14: β-carotene isomerase

EC 5.3: Intramolecular Oxidoreductases

EC 5.3.1: Interconverting Aldoses and Ketoses

EC 5.3.1.1: triose-phosphate isomerase
EC 5.3.1.2: deleted
EC 5.3.1.3: D-arabinose isomerase
EC 5.3.1.4: L-arabinose isomerase
EC 5.3.1.5: xylose isomerase
EC 5.3.1.6: ribose-5-phosphate isomerase
EC 5.3.1.7: mannose isomerase
EC 5.3.1.8: mannose-6-phosphate isomerase
EC 5.3.1.9: glucose-6-phosphate isomerase
EC 5.3.1.10: Now EC 3.5.99.6, glucosamine-6-phosphate deaminase
EC 5.3.1.11: deleted
EC 5.3.1.12: glucuronate isomerase
EC 5.3.1.13: arabinose-5-phosphate isomerase
EC 5.3.1.14: L-rhamnose isomerase
EC 5.3.1.15: D-lyxose ketol-isomerase
EC 5.3.1.16: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
EC 5.3.1.17: 5-dehydro-4-deoxy-D-glucuronate isomerase
EC 5.3.1.18: deleted: reaction is due to EC 5.3.1.9 glucose-6-phosphate isomerase, in the presence of arsenate, or EC 5.3.1.5 xylose isomerase
EC 5.3.1.19: Now EC 2.6.1.16, glutamine—fructose-6-phosphate transaminase (isomerizing)
EC 5.3.1.20: ribose isomerase
EC 5.3.1.21: corticosteroid side-chain-isomerase
EC 5.3.1.22: hydroxypyruvate isomerase
EC 5.3.1.23: S-methyl-5-thioribose-1-phosphate isomerase
EC 5.3.1.24: phosphoribosylanthranilate isomerase
EC 5.3.1.25: L-fucose isomerase
EC 5.3.1.26: galactose-6-phosphate isomerase
EC 5.3.1.27: 6-phospho-3-hexuloisomerase
EC 5.3.1.28: D-sedoheptulose 7-phosphate isomerase
EC 5.3.1.29: ribose 1,5-bisphosphate isomerase *
EC 5.3.1.30: 5-deoxy-glucuronate isomerase *
EC 5.3.1.31: sulfoquinovose isomerase *
EC 5.3.1.32: (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase *
EC 5.3.1.33: L-erythrulose 1-phosphate isomerase *
EC 5.3.1.34: D-erythrulose 4-phosphate isomerase *
EC 5.3.1.35: 2-dehydrotetronate isomerase *
EC 5.3.1.36: D-apiose isomerase *

*No Wikipedia article

EC 5.3.2: Interconverting Keto- and Enol-Groups

EC 5.3.3: Transposing C=C Bonds

EC 5.3.3.1: steroid Δ-isomerase
EC 5.3.3.2: isopentenyl-diphosphate Δ-isomerase
EC 5.3.3.3: vinylacetyl-CoA Δ-isomerase
EC 5.3.3.4: muconolactone Δ-isomerase
EC 5.3.3.5: cholestenol Δ-isomerase
EC 5.3.3.6: methylitaconate Δ-isomerase
EC 5.3.3.7: aconitate Δ-isomerase
EC 5.3.3.8: Δ³-Δ²-enoyl-CoA isomerase
EC 5.3.3.9: prostaglandin-A₁ Δ-isomerase
EC 5.3.3.10: 5-carboxymethyl-2-hydroxymuconate Δ-isomerase
EC 5.3.3.11: isopiperitenone Δ-isomerase
EC 5.3.3.12: L-dopachrome isomerase
EC 5.3.3.13: polyenoic fatty acid isomerase
EC 5.3.3.14: trans-2-decenoyl-[acyl-carrier protein] isomerase
EC 5.3.3.15: Now EC 5.3.2.7, ascopyrone tautomerase
EC 5.3.3.16: Now EC 5.3.2.8, 4-oxalomesaconate tautomerase
EC 5.3.3.17: trans-2,3-dihydro-3-hydroxyanthranilate isomerase
EC 5.3.3.18: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase
EC 5.3.3.19: 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase *
EC 5.3.3.20: Now EC 5.4.99.64, 2-hydroxyisobutanoyl-CoA mutase
EC 5.3.3.21: Δ^3,5-Δ^2,4-dienoyl-CoA isomerase *
EC 5.3.3.22: lutein isomerase *
EC 5.3.3.23: S-methyl-5-thioribulose 1-phosphate isomerase *

*No Wikipedia article

EC 5.3.4: Transposing S-S Bonds

EC 5.3.4.1: protein disulfide-isomerase

EC 5.3.99: Other Intramolecular Oxidoreductases

EC 5.3.99.1: deleted, reaction due to combined action of EC 4.2.1.92 (hydroperoxide dehydratase) and EC 5.3.99.6 (allene-oxide cyclase)
EC 5.3.99.2: prostaglandin-D synthase
EC 5.3.99.3: prostaglandin-E synthase
EC 5.3.99.4: prostaglandin-I synthase
EC 5.3.99.5: thromboxane-A synthase
EC 5.3.99.6: allene-oxide cyclase
EC 5.3.99.7: styrene-oxide isomerase
EC 5.3.99.8: capsanthin/capsorubin synthase
EC 5.3.99.9: neoxanthin synthase
EC 5.3.99.10: thiazole tautomerase
EC 5.3.99.11: 2-keto-myo-inositol isomerase *

*No Wikipedia article

EC 5.4: Intramolecular Transferases

EC 5.4.1: Transferring Acyl Groups

EC 5.4.1.1: lysolecithin acylmutase
EC 5.4.1.2: Now EC 5.4.99.61, precorrin-8X methylmutase
EC 5.4.1.3: 2-methylfumaryl-CoA isomerase *
EC 5.4.1.4: D-galactarolactone isomerase *

*No Wikipedia article

EC 5.4.2: Phosphotransferases (Phosphomutases)

EC 5.4.2.1: Now recognized as two separate enzymes EC 5.4.2.11, phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) and EC 5.4.2.12, phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
EC 5.4.2.2: phosphoglucomutase (α-D-glucose-1,6-bisphosphate-dependent)
EC 5.4.2.3: phosphoacetylglucosamine mutase
EC 5.4.2.4: bisphosphoglycerate mutase
EC 5.4.2.5: phosphoglucomutase (glucose-cofactor)
EC 5.4.2.6: β-phosphoglucomutase
EC 5.4.2.7: phosphopentomutase
EC 5.4.2.8: phosphomannomutase
EC 5.4.2.9: phosphoenolpyruvate mutase
EC 5.4.2.10: phosphoglucosamine mutase
EC 5.4.2.11: phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
EC 5.4.2.12: phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
EC 5.4.2.13: phosphogalactosamine mutase *

*No Wikipedia article

EC 5.4.3: Transferring Amino Groups

EC 5.4.3.1: deleted; this reaction was due to a mixture of EC 5.1.1.12 (ornithine racemase) and EC 5.4.3.5 (D-ornithine 4,5-aminomutase)
EC 5.4.3.2: lysine 2,3-aminomutase
EC 5.4.3.3: lysine 5,6-aminomutase
EC 5.4.3.4: Now included in EC 5.4.3.3, lysine 5,6-aminomutase
EC 5.4.3.5: D-ornithine 4,5-aminomutase
EC 5.4.3.6: tyrosine 2,3-aminomutase
EC 5.4.3.7: leucine 2,3-aminomutase
EC 5.4.3.8: glutamate-1-semialdehyde 2,1-aminomutase
EC 5.4.3.9: glutamate 2,3-aminomutase
EC 5.4.3.10: phenylalanine aminomutase (L-β-phenylalanine forming) *
EC 5.4.3.11: phenylalanine aminomutase (D-β-phenylalanine forming) *

*No Wikipedia article

EC 5.4.4: Transferring hydroxy groups

EC 5.4.4.1: (hydroxyamino)benzene mutase
EC 5.4.4.2: isochorismate synthase
EC 5.4.4.3: 3-(hydroxyamino)phenol mutase
EC 5.4.4.4: geraniol isomerase
EC 5.4.4.5: 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
EC 5.4.4.6: 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase
EC 5.4.4.7: hydroperoxy icosatetraenoate isomerase *
EC 5.4.4.8: linalool isomerase *

*No Wikipedia article

EC 5.4.99: Transferring Other Groups

EC 5.4.99.1: methylaspartate mutase
EC 5.4.99.2: methylmalonyl-CoA mutase
EC 5.4.99.3: 2-acetolactate mutase
EC 5.4.99.4: 2-methyleneglutarate mutase
EC 5.4.99.5: chorismate mutase
EC 5.4.99.6: Now EC 5.4.4.2, isochorismate synthase
EC 5.4.99.7: lanosterol synthase
EC 5.4.99.8: cycloartenol synthase
EC 5.4.99.9: UDP-galactopyranose mutase
EC 5.4.99.10: Now included with EC 5.4.99.11, isomaltulose synthase
EC 5.4.99.11: isomaltulose synthase
EC 5.4.99.12: tRNA pseudouridine^38-40 synthase
EC 5.4.99.13: isobutyryl-CoA mutase
EC 5.4.99.14: 4-carboxymethyl-4-methylbutenolide mutase
EC 5.4.99.15: (1→4)-α-D-glucan 1-α-D-glucosylmutase
EC 5.4.99.16: maltose α-D-glucosyltransferase
EC 5.4.99.17: squalene—hopene cyclase
EC 5.4.99.18: 5-(carboxyamino)imidazole ribonucleotide mutase
EC 5.4.99.19: 16S rRNA pseudouridine⁵¹⁶ synthase
EC 5.4.99.20: 23S rRNA pseudouridine²⁴⁵⁷ synthase
EC 5.4.99.21: 23S rRNA pseudouridine²⁶⁰⁴ synthase
EC 5.4.99.22: 23S rRNA pseudouridine²⁶⁰⁵ synthase
EC 5.4.99.23: 23S rRNA pseudouridine^{1911/1915/1917} synthase
EC 5.4.99.24: 23S rRNA pseudouridine^{955/2504/2580} synthase
EC 5.4.99.25: tRNA pseudouridine⁵⁵ synthase
EC 5.4.99.26: tRNA pseudouridine⁶⁵ synthase
EC 5.4.99.27: tRNA pseudouridine¹³ synthase
EC 5.4.99.28: RNA pseudouridine³² synthase
EC 5.4.99.29: 23S rRNA pseudouridine⁷⁴⁶ synthase
EC 5.4.99.30: UDP-arabinopyranose mutase
EC 5.4.99.31: thalianol synthase
EC 5.4.99.32: protostadienol synthase
EC 5.4.99.33: cucurbitadienol synthase
EC 5.4.99.34: germanicol synthase
EC 5.4.99.35: taraxerol synthase
EC 5.4.99.36: isomultiflorenol synthase
EC 5.4.99.37: dammaradiene synthase
EC 5.4.99.38: camelliol C synthase
EC 5.4.99.39: β-amyrin synthase
EC 5.4.99.40: α-amyrin synthase
EC 5.4.99.41: lupeol synthase
EC 5.4.99.42: tRNA pseudouridine³¹ synthase
EC 5.4.99.43: 21S rRNA pseudouridine²⁸¹⁹ synthase
EC 5.4.99.44: mitochondrial tRNA pseudouridine^27/28 synthase
EC 5.4.99.45: tRNA pseudouridine^38/39 synthase
EC 5.4.99.46: shionone synthase
EC 5.4.99.47: parkeol synthase
EC 5.4.99.48: achilleol B synthase
EC 5.4.99.49: glutinol synthase
EC 5.4.99.50: friedelin synthase
EC 5.4.99.51: baccharis oxide synthase
EC 5.4.99.52: α-seco-amyrin synthase
EC 5.4.99.53: marneral synthase
EC 5.4.99.54: β-seco-amyrin synthase
EC 5.4.99.55: δ-amyrin synthase
EC 5.4.99.56: tirucalladienol synthase
EC 5.4.99.57: baruol synthase
EC 5.4.99.58: methylornithine synthase
EC 5.4.99.59: dTDP-fucopyranose mutase *
EC 5.4.99.60: cobalt-precorrin-8 methylmutase *
EC 5.4.99.61: precorrin-8X methylmutase *
EC 5.4.99.62: D-ribose pyranase *
EC 5.4.99.63: ethylmalonyl-CoA mutase *
EC 5.4.99.64: 2-hydroxyisobutanoyl-CoA mutase *
EC 5.4.99.65: pre-α-onocerin synthase *
EC 5.4.99.66: α-onocerin synthase *
EC 5.4.99.67: 4-amino-4-deoxychorismate mutase *

*No Wikipedia article

EC 5.5: Intramolecular Lyases

EC 5.5.1: Intramolecular lyases (only sub-subclass identified to date)

EC 5.5.1.1: muconate cycloisomerase
EC 5.5.1.2: 3-carboxy-cis,cis-muconate cycloisomerase
EC 5.5.1.3: tetrahydroxypteridine cycloisomerase
EC 5.5.1.4: inositol-3-phosphate synthase
EC 5.5.1.5: carboxy-cis,cis-muconate cyclase
EC 5.5.1.6: chalcone isomerase
EC 5.5.1.7: chloromuconate cycloisomerase
EC 5.5.1.8: (+)-bornyl diphosphate synthase
EC 5.5.1.9: cycloeucalenol cycloisomerase
EC 5.5.1.10: α-pinene-oxide decyclase
EC 5.5.1.11: dichloromuconate cycloisomerase
EC 5.5.1.12: copalyl diphosphate synthase
EC 5.5.1.13: ent-copalyl diphosphate synthase
EC 5.5.1.14: syn-copalyl-diphosphate synthase
EC 5.5.1.15: terpentedienyl-diphosphate synthase
EC 5.5.1.16: halimadienyl-diphosphate synthase
EC 5.5.1.17: (S)-β-macrocarpene synthase
EC 5.5.1.18: lycopene ε-cyclase
EC 5.5.1.19: lycopene β-cyclase
EC 5.5.1.20: prosolanapyrone-III cycloisomerase
EC 5.5.1.21: copal-8-ol diphosphate synthase. The enzyme was discovered at the public-review stage to have been misclassified and so was withdrawn. See EC 4.2.1.133, copal-8-ol diphosphate hydratase
EC 5.5.1.22: (–)-bornyl diphosphate synthase *
EC 5.5.1.23: aklanonic acid methyl ester cyclase *
EC 5.5.1.24: tocopherol cyclase *
EC 5.5.1.25: 3,6-anhydro-L-galactonate cycloisomerase *
EC 5.5.1.26: nogalonic acid methyl ester cyclase *
EC 5.5.1.27: D-galactarolactone cycloisomerase *
EC 5.5.1.28: (–)-kolavenyl diphosphate synthase *
EC 5.5.1.29: (+)-kolavenyl diphosphate synthase *
EC 5.5.1.30: labda-7,13-dienyl diphosphate synthase *
EC 5.5.1.31: hapalindole H synthase *
EC 5.5.1.32: 12-epi-hapalindole U synthase *
EC 5.5.1.33: 12-epi-fischerindole U synthase *
EC 5.5.1.34: (+)-cis,trans-nepetalactol synthase *
EC 5.5.1.35: (+)-cis,cis-nepetalactol synthase *

*No Wikipedia article

EC 5.6: Isomerases altering macromolecular conformation

EC 5.6.1: Enzymes altering polypeptide conformation or assembly

EC 5.6.1.1: microtubule-severing ATPase
EC 5.6.1.2: dynein ATPase
EC 5.6.1.3: plus-end-directed kinesin ATPase
EC 5.6.1.4: minus-end-directed kinesin ATPase
EC 5.6.1.5: proteasome ATPase
EC 5.6.1.6: channel-conductance-controlling ATPase
EC 5.6.1.7: chaperonin ATPase
EC 5.6.1.8: myosin ATPase
EC 5.6.1.9: (R)-2-hydroxyacyl-CoA dehydratase activating ATPase *

*No Wikipedia article

EC 5.6.2: Enzymes altering nucleic acid conformation

EC 5.6.2.1: DNA topoisomerase
EC 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing)
EC 5.6.2.3: DNA 5'-3' helicase
EC 5.6.2.4: DNA 3'-5' helicase

EC 5.99: Other Isomerases

EC 5.99.1: Sole sub-subclass for isomerases that do not belong in the other subclasses

EC 5.99.1.1: thiocyanate isomerase
EC 5.99.1.2: Now EC 5.6.2.1, DNA topoisomerase
EC 5.99.1.3: Now EC 5.6.2.2, DNA topoisomerase (ATP-hydrolysing)
EC 5.99.1.4: 2-hydroxychromene-2-carboxylate isomerase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

v t e Isomerases: Epimerase and racemases (EC 5.1)
5.1.1: Amino acids	Amino-acid racemase: Phenylalanine racemase (ATP-hydrolysing) Serine racemase
5.1.2: Hydroxy acids	Mandelate racemase Isocitrate epimerase
5.1.3: Carbohydrates	UDP-glucose 4-epimerase N-acetylneuraminate epimerase Phosphopentose epimerase
5.1.99: Other	Methylmalonyl CoA epimerase

v t e Isomerases: intramolecular oxidoreductases (EC 5.3)
5.3.1: Aldoses/Ketoses	Triosephosphate isomerase Ribose-5-phosphate isomerase Mannose phosphate isomerase Glucose isomerase
5.3.2: Keto/Enol	Phenylpyruvate tautomerase Oxaloacetate tautomerase 4-Oxalocrotonate tautomerase
5.3.3: C = C	Steroid D-isomerase Isopentenyl-diphosphate delta isomerase Vinylacetyl-CoA D-isomerase Muconolactone D-isomerase Cholestenol Delta-isomerase (EBP) Methylitaconate D-isomerase Aconitate Delta-isomerase Enoyl CoA isomerase Prostaglandin-A1 Delta-isomerase 5-carboxymethyl-2-hydroxymuconate D-isomerase Isopiperitenone D-isomerase L-dopachrome isomerase Polyenoic fatty acid isomerase
5.3.4: S-S	Protein disulfide-isomerase (PDIA3)
5.3.99: other	Prostaglandin D2 synthase/Prostaglandin-D synthase Prostaglandin E synthase Prostacyclin synthase Thromboxane-A synthase

v t e Isomerase: mutases (EC 5.4)
5.4.1 Acyl Groups	Lysolecithin acylmutase Precorrin-8X methylmutase
5.4.2 Phosphomutases	Phosphoglycerate mutase Bisphosphoglycerate mutase Phosphoglucomutase Phosphomannomutase PMM1 PMM2 Phosphoenolpyruvate mutase
5.4.99 Other groups	Cycloartenol synthase Lanosterol synthase Lupeol synthase Methylmalonyl-CoA mutase

Isomerase: Intramolecular Lyases (EC 5.5)

5.5.1 Intramolecular Lyases

References

^ "ExplorEnz – The Enzyme Database".
^ McDonald, A.G.; Boyce, S.; K.F., Tipton (2009). "ExplorEnz: the primary source of the IUBMB enzyme list". Nucleic Acids Res. 37: D593–D597. doi:10.1093/nar/gkn582. PMC 2686581.

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