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2CB-5OCD3

2CB-5OCD3
Clinical data
Other names2C-B-5-OCD3; 5-Trideuteromethoxy-2C-B; 4-Bromo-2-methoxy-5-trideuteromethoxyphenethylamine; 2-(4-Bromo-2-methoxy-5-(methoxy-d3)phenyl)ethan-1-amine
Drug classSerotonin 5-HT2A receptor agonist; Possible serotonergic psychedelic or hallucinogen
ATC code
  • None
Identifiers
  • 2-[4-bromo-2-methoxy-5-(trideuteriomethoxy)phenyl]ethanamine
PubChem CID
Chemical and physical data
FormulaC10H14BrNO2
Molar mass260.131 g·mol−1
3D model (JSmol)
  • [2H]C([2H])([2H])OC1=C(C=C(C(=C1)CCN)OC)Br
  • InChI=1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3/i2D3
  • Key:YMHOBZXQZVXHBM-BMSJAHLVSA-N

2CB-5OCD3, also known as 5-trideuteromethoxy-2C-B, is a serotonin 5-HT2A receptor agonist and possible psychedelic drug of the phenethylamine and 2C families.[1][2] It is the isotopologue of 2C-B in which the three hydrogen atoms of the methoxy group at the 5 position have been replaced with the deuterium isotopes.[1][2] The drug shows similar serotonin 5-HT2A receptor pharmacodynamics and metabolism as 2C-B in vitro.[1][2] The chemical synthesis of 2CB-5OCD3 has been described.[1][2] 2CB-5OCD3 was developed by Nicholas V. Cozzi and Paul F. Daley of the Alexander Shulgin Research Institute (ASRI).[1][2] It was patented in 2024[2] and was first described in the scientific literature in 2026.[1]

See also

References

  1. ^ a b c d e f Cozzi NV (June 2026). "Serotonin 2A receptor binding, functional activity, and in vitro metabolism of two trideuteromethoxy 2C-B isotopologues". Naunyn-Schmiedeberg's Archives of Pharmacology. doi:10.1007/s00210-026-05566-5. PMID 42313138.
  2. ^ a b c d e f US 20240408038, Daley PF, Cozzi NV, "Substituted phenylalkylamines", published 2024-12-12, issued 2025-11-11, assigned to Alexander Shulgin Research Institute Inc 
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