1917年9月13日,UC-21号从泽布吕赫出发,前往比斯开湾执行布雷巡逻。三天后,即9月16日,时任指挥官维尔纳·冯·策伯尼·迪·斯波塞蒂中尉率部在韦桑岛对开约30海里(56公里)处截停并凿沉了美国帆船安·J·特雷纳号(Ann J. Trainer)。[15]在此之后,UC-21号便连同艇内27名官兵失去了踪迹。据推测,它可能是遭敌舰击沉,也可能是因机件故障或人为错误而导致了海损(德语:Havarie)。[1]
^Helgason, Guðmundur. Most Successful U-boats. German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. [2022-03-17]. (原始内容存档于2019-09-15).
^ 11.011.1Helgason, Guðmundur. Ships hit by UC 21. German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. [2014-12-12].
^Helgason, Guðmundur. Ships hit during WWI: Illinois. German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. [2022-08-09].
^Helgason, Guðmundur. Ships hit during WWI: HMS Ferret. German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. [2022-08-09].
^Helgason, Guðmundur. Ships hit during WWI: Roelfina. German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. [2022-08-09].
^Helgason, Guðmundur. Ships hit during WWI: Ann J. Trainer. German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. [2022-08-09].