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GPR161
Identifiers
Aliases	GPR161, RE2, G protein-coupled receptor 161
External IDs	OMIM: 612250; MGI: 2685054; HomoloGene: 17824; GeneCards: GPR161; OMA:GPR161 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	168,137,667 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	165,154,314 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; myometrium; ; buccal mucosa cell; ; ventricular zone; ; tail of epididymis; ; body of uterus; ; pars reticulata; ; stromal cell of endometrium; ; spinal ganglia; ; pars compacta;
	Top expressed in
	subiculum; ; otic vesicle; ; Region I of hippocampus proper; ; ganglionic eminence; ; hand; ; lumbar spinal ganglion; ; morula; ; medial ganglionic eminence; ; hippocampus proper; ; ascending aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	plasma membrane; cell projection; membrane; ciliary membrane; integral component of membrane; endocytic vesicle membrane; cilium; recycling endosome;
Biological process	multicellular organism development; signal transduction; G protein-coupled receptor signaling pathway; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning; adenylate cyclase-activating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	23432
	240888
	ENSG00000143147
	ENSMUSG00000040836
	Q8N6U8
	B2RPY5
NM_001267609; NM_001267610; NM_001267611; NM_001267612; NM_001267613;
	NM_001267614; NM_007369; NM_153832; NM_001349632; NM_001349633; NM_001349634; NM_001349635; NM_001375883; NM_001375884; NM_001375885; NM_001381909
	NM_001081126; NM_001310429; NM_001310430
NP_001254538; NP_001254539; NP_001254540; NP_001254541; NP_001254542;
	NP_001254543; NP_722561; NP_001336561; NP_001336562; NP_001336563; NP_001336564; NP_001362812; NP_001362813; NP_001362814; NP_001368838
	NP_001074595; NP_001297358; NP_001297359
	Wikidata
View/Edit Human	View/Edit Mouse

G-protein coupled receptor 161 is a protein that in humans is encoded by the GPR161 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143147 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040836 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Small KM, Seman CA, Castator A, Brown KM, Liggett SB (Apr 2002). "False positive non-synonymous polymorphisms of G-protein coupled receptor genes". FEBS Lett. 516 (1–3): 253–6. doi:10.1016/S0014-5793(02)02564-4. PMID 11959142. S2CID 35944696.
^ "Entrez Gene: GPR161 G protein-coupled receptor 161".

Schöneberg T, Schulz A, Gudermann T (2002). "The structural basis of G-protein-coupled receptor function and dysfunction in human diseases". Rev. Physiol. Biochem. Pharmacol. Reviews of Physiology, Biochemistry and Pharmacology. 144: 143–227. doi:10.1007/BFb0116587. ISBN 978-3-540-42814-5. PMID 11987825.
Raming K, Konzelmann S, Breer H (1999). "Identification of a novel G-protein coupled receptor expressed in distinct brain regions and a defined olfactory zone". Recept. Channels. 6 (2): 141–51. PMID 9932290.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143147 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040836 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11959142-5] Small KM, Seman CA, Castator A, Brown KM, Liggett SB (Apr 2002). "False positive non-synonymous polymorphisms of G-protein coupled receptor genes". FEBS Lett. 516 (1–3): 253–6. doi:10.1016/S0014-5793(02)02564-4. PMID 11959142. S2CID 35944696.

[entrez-6] "Entrez Gene: GPR161 G protein-coupled receptor 161".

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GPR161

References

Further reading