Mixed doubles
2021 Australian Open
Final
Champions	Barbora Krejčíková Rajeev Ram
Runners-up	Samantha Stosur Matthew Ebden
Score	6–1, 6–4
Details
Seeds	8
Events
Singles men women boys girls Doubles men women mixed boys girls WC Singles men women quad WC Doubles men women quad Legends men women mixed
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Two-time defending champion Barbora Krejčíková and her partner Rajeev Ram defeated Samantha Stosur and Matthew Ebden in the final, 6–1, 6–4 to win the mixed doubles tennis title at the 2021 Australian Open. It was the pair's second major mixed doubles title as a team, after their first at the 2019 Australian Open. They saved a match point en route to the title, in the second round against Ena Shibahara and Ben McLachlan.^[1]

Krejčíková and Nikola Mektić were the defending champions,^[2] but chose to play separately this year. Mektić partnered Barbora Strýcová, but was defeated in the first round by Hayley Carter and Sander Gillé.

After not being held at the 2020 US Open and postponed 2020 French Open due to the COVID-19 pandemic, this year's tournament marked the return of mixed doubles to a Grand Slam tournament.^[3]

	Semifinals							Final
	WC	Samantha Stosur Matthew Ebden	7	5	[10]
		Desirae Krawczyk Joe Salisbury	5	7	[8]
								WC	Samantha Stosur Matthew Ebden	1	4
								6	Barbora Krejčíková Rajeev Ram	6	6
	6	Barbora Krejčíková Rajeev Ram	6	6
	WC	Storm Sanders Marc Polmans	3	3

	First round							Second round							Quarterfinals							Semifinals
	1	B Strýcová N Mektić	4	7	[4]
	Alt	H Carter S Gillé	6	5	[10]			Alt	H Carter S Gillé	6	6
		I Świątek Ł Kubot	5	78	[10]				I Świątek Ł Kubot	4	1
	WC	A Sharma J-P Smith	7	66	[6]										Alt	H Carter S Gillé	3	2
	WC	S Stosur M Ebden	6	6											WC	S Stosur M Ebden	6	6
		E Rybakina A Bublik	1	4				WC	S Stosur M Ebden	6	6
		J Ostapenko M Middelkoop	5	4				8	L Stefani B Soares	3	1
	8	L Stefani B Soares	7	6																		WC	S Stosur M Ebden	7	5	[10]
	4	H-c Chan JS Cabal	4	6	[7]																		D Krawczyk J Salisbury	5	7	[8]
		D Krawczyk J Salisbury	6	3	[10]				D Krawczyk J Salisbury	6	6
		Y Xu M González	6	3	[7]				V Zvonareva M Melo	4	4
		V Zvonareva M Melo	4	6	[10]											D Krawczyk J Salisbury	6	6
	WC	B Woolcock J Peers	2	7	[10]											A Klepač N Skupski	3	4
		A Klepač N Skupski	6	5	[12]				A Klepač N Skupski	63	77	[10]
		L Hradecká F Polášek	6	7					L Hradecká F Polášek	77	65	[8]
	7	L Chan I Dodig	4	5

	First round							Second round							Quarterfinals							Semifinals
	6	B Krejčíková R Ram	78	7
		Y Shvedova H Kontinen	66	5				6	B Krejčíková R Ram	6	3	[13]
		L Siegemund K Krawietz	63	4					E Shibahara B McLachlan	4	6	[11]
		E Shibahara B McLachlan	77	6											6	B Krejčíková R Ram	77	6
		B Mattek-Sands J Murray	6	6											3	G Dabrowski M Pavić	63	3
		Y Duan R Bopanna	4	4					B Mattek-Sands J Murray	67	7	[3]
	WC	I Popovic A Vukic	1	1				3	G Dabrowski M Pavić	79	5	[10]
	3	G Dabrowski M Pavić	6	6																		6	B Krejčíková R Ram	6	6
	5	D Schuurs W Koolhof	3	6	[9]																	WC	S Sanders M Polmans	3	3
	WC	S Sanders M Polmans	6	3	[11]			WC	S Sanders M Polmans	6	64	[10]
	WC	E Perez A Harris	7	78				WC	E Perez A Harris	4	77	[8]
	WC	A Muhammad L Saville	5	66											WC	S Sanders M Polmans	4	7	[10]
	WC	Ar Rodionova M Purcell	7	6											WC	Ar Rodionova M Purcell	6	5	[8]
		A Guarachi M Venus	5	4				WC	Ar Rodionova M Purcell	w/o
		C Dolehide F Martin	4	4				2	N Melichar R Farah
	2	N Melichar R Farah	6	6

• 2021 Australian Open – Day-by-day summaries

• 2021 Australian Open – Doubles draws and results at the International Tennis Federation
• Main draw