Men's singles
2021 Italian Open
Final
Champion	Rafael Nadal
Runner-up	Novak Djokovic
Score	7–5, 1–6, 6–3
Details
Draw	56 (8 Q / 5 WC )
Seeds	16
Events
Singles men women Doubles men women
← 2020 · Italian Open · 2022 →

Rafael Nadal defeated the defending champion Novak Djokovic in the final, 7–5, 1–6, 6–3 to win the men's singles tennis title at the 2021 Italian Open.^[1] It was his record-extending tenth Italian Open title and record-equaling 36th and final Masters 1000 title overall (matching Djokovic's tally). Nadal saved two match points en route to the title, in his third round match against Denis Shapovalov.^[2] This marked the fourth tournament that Nadal had won on 10 or more occasions (in addition to the French Open, the Monte-Carlo Masters, and the Barcelona Open), making him the only tennis player to do so.^[3]

It was Djokovic's sixth runners-up finish at the Italian Open, a record for the most runners-up finishes at one event on the ATP Tour. (Djokovic equaled this record later that year at the US Open, while attempting to complete the Grand Slam).^[4]

Lorenzo Sonego became the first Italian man to reach the semifinals in Rome since Filippo Volandri in 2007.^[5]

The top eight seeds received a bye into the second round.

Click on the seed number of a player to go to their draw section.

	Quarterfinals							Semifinals							Final
	1	Novak Djokovic	4	7	7
	5	Stefanos Tsitsipas	6	5	5
								1	Novak Djokovic	6	65	6
									Lorenzo Sonego	3	77	2
		Lorenzo Sonego	3	6	6
	7	Andrey Rublev	6	4	3
															1	Novak Djokovic	5	6	3
															2	Rafael Nadal	7	1	6
	Q	Federico Delbonis	5	62
		Reilly Opelka	7	77
									Reilly Opelka	4	4
								2	Rafael Nadal	6	6
	6	Alexander Zverev	3	4
	2	Rafael Nadal	6	6

	First round							Second round							Third round							Quarterfinals
								1	N Djokovic	6	77
		D Evans	3	2					T Fritz	3	65
		T Fritz	6	6											1	N Djokovic	6	6
	Q	R Carballés Baena	4	4											Q	A Davidovich Fokina	2	1
	Q	C Norrie	6	6				Q	C Norrie	2	3
	Q	A Davidovich Fokina	6	77				Q	A Davidovich Fokina	6	6
	16	G Dimitrov	4	62																		1	N Djokovic	4	7	7
	9	M Berrettini	4	6	6																	5	S Tsitsipas	6	5	5
		N Basilashvili	6	2	4			9	M Berrettini	6	6
		J Millman	6	6					J Millman	4	2
		D Lajović	3	4											9	M Berrettini	63	2
		M Čilić	4	6	6										5	S Tsitsipas	77	6
		A Bublik	6	2	3				M Čilić	5	2
								5	S Tsitsipas	7	6

	First round							Second round							Third round							Quarterfinals
								4	D Thiem	3	77	6
	LL	Y Nishioka	0	2					M Fucsovics	6	65	0
		M Fucsovics	6	6											4	D Thiem	4	77	65
	WC	G Mager	6	6												L Sonego	6	65	77
		A de Minaur	4	3				WC	G Mager	4	4
		L Sonego	6	5	6				L Sonego	6	6
	14	G Monfils	4	7	4																		L Sonego	3	6	6
	10	R Bautista Agut	6	6																		7	A Rublev	6	4	3
	Q	T Paul	3	4				10	R Bautista Agut	77	6
		L Harris	5	2					C Garín	65	3
		C Garín	7	6											10	R Bautista Agut	4	4
	LL	A Bedene	3	1											7	A Rublev	6	6
		J-L Struff	6	6					J-L Struff	79	1	4
								7	A Rublev	67	6	6

	First round							Second round							Third round							Quarterfinals
								8	D Schwartzman	1	3
		F Krajinović	3	77	4				F Auger-Aliassime	6	6
		F Auger-Aliassime	6	65	6											F Auger-Aliassime	63	1
		K Khachanov	6	4	0										Q	F Delbonis	77	6
	Q	F Delbonis	3	6	6			Q	F Delbonis	6	6
	WC	S Caruso	4	1				12	D Goffin	2	1
	12	D Goffin	6	6																		Q	F Delbonis	5	62
	15	H Hurkacz	4	0r																			R Opelka	7	77
	WC	L Musetti	6	2				WC	L Musetti	4	4
		R Gasquet	1	5					R Opelka	6	6
		R Opelka	6	7												R Opelka	78	6
		M Kecmanović	62	4												A Karatsev	66	4
		A Karatsev	77	6					A Karatsev	6	6
								3	D Medvedev	2	4

	First round							Second round							Third round							Quarterfinals
								6	A Zverev	6	6
	Q	H Dellien	2	7	6			Q	H Dellien	2	2
		A Mannarino	6	5	2										6	A Zverev	4	6	6
		K Nishikori	6	6												K Nishikori	6	3	4
		F Fognini	3	4					K Nishikori	w/o
		L Đere	6	3	1			11	P Carreño Busta
	11	P Carreño Busta	4	6	6																	6	A Zverev	3	4
	13	D Shapovalov	6	6																		2	R Nadal	6	6
	Q	K Majchrzak	1	3				13	D Shapovalov	77	6
	WC	S Travaglia	6	6				WC	S Travaglia	62	3
		B Paire	4	3											13	D Shapovalov	6	4	63
		U Humbert	2	4											2	R Nadal	3	6	77
		J Sinner	6	6					J Sinner	5	4
								2	R Nadal	7	6

	First round							Qualifying competition
	1	Cameron Norrie	6	6
		Pablo Cuevas	1	3
								1	Cameron Norrie	6	2	6
									Marco Cecchinato	4	6	4
		Marco Cecchinato	64	6	6
	9	Egor Gerasimov	77	2	3

	First round							Qualifying competition
	2	Alejandro Davidovich Fokina	6	2
	WC	Flavio Cobolli	2	0r
								2	Alejandro Davidovich Fokina	6	77
								8	Corentin Moutet	4	65
	WC	Andrea Pellegrino	65	2
	8	Corentin Moutet	77	6

	First round							Qualifying competition
	3	Aljaž Bedene	6	3	6
	WC	Gian Marco Moroni	2	6	4
								3	Aljaž Bedene	2	1
									Hugo Dellien	6	6
		Hugo Dellien	6	6
	14	Jaume Munar	4	1

	First round							Qualifying competition
	4	Tommy Paul	77	6
		Juan Ignacio Londero	65	3
								4	Tommy Paul	7	4	77
								12	Thiago Monteiro	5	6	64
		Mikhail Kukushkin	63	61
	12	Thiago Monteiro	77	77

	First round							Qualifying competition
	5	Yoshihito Nishioka	6	77
		Grégoire Barrère	4	61
								5	Yoshihito Nishioka	3	1
									Kamil Majchrzak	6	6
		Kamil Majchrzak	78	64	6
	10	Alexei Popyrin	66	77	3

	First round							Qualifying competition
	6	Tennys Sandgren	5	3
		Roberto Carballés Baena	7	6
									Roberto Carballés Baena	7	6
								WC	Raúl Brancaccio	5	4
	WC	Raúl Brancaccio	3	6	6
	Alt	Federico Gaio	6	4	4

	First round							Qualifying competition
	7	Frances Tiafoe	6	7
		Jozef Kovalík	2	5
								7	Frances Tiafoe	7	4	2r
								11	Federico Delbonis	5	6	4
		Marcos Giron	3	3
	11	Federico Delbonis	6	6

The following are the seeded players. Seedings are based on ATP rankings as of 3 May 2021. Rankings and points before are as of 10 May 2021.

Seed	Rank	Player	Points before	Points defending[a]	Points won	Points after	Status
1	1	Novak Djokovic	11,463	1,000	600	11,063	Runner-up, lost to Rafael Nadal [2]
2	3	Rafael Nadal	9,630	1,000	1,000	9,630	Champion, defeated Novak Djokovic [1]
3	2	Daniil Medvedev	9,780	10	45	9,815	Second round lost to Aslan Karatsev
4	4	Dominic Thiem	8,365	10	90	8,445	Third round lost to Lorenzo Sonego
5	5	Stefanos Tsitsipas	7,610	360	180	7,430	Quarterfinals lost to Novak Djokovic [1]
6	6	Alexander Zverev	6,945	10	180	7,115	Quarterfinals lost to Rafael Nadal [2]
7	7	Andrey Rublev	6,000	90	180	6,090	Quarterfinals lost to Lorenzo Sonego
8	10	Diego Schwartzman	3,765	345	45	3,465	Second round lost to Félix Auger-Aliassime
9	9	Matteo Berrettini	4,048	180	90	3,958	Third round lost to Stefanos Tsitsipas [5]
10	11	Roberto Bautista Agut	3,170	0	45	3,215	Third round lost to Andrey Rublev [7]
11	12	Pablo Carreño Busta	3,050	10	45	3,085	Second round, withdrew due to a low back injury
12	13	David Goffin	2,875	45	45	2,875	Second round lost to Federico Delbonis [Q]
13	14	Denis Shapovalov	2,855	360	180	2,675	Third round lost to Rafael Nadal [2]
14	15	Gaël Monfils	2,703	10	10	2,703	First round lost to Lorenzo Sonego
15	19	Hubert Hurkacz	2,543	55	10	2,498	First round retired against Lorenzo Musetti [WC]
16	17	Grigor Dimitrov	2,586	90	0	2,496	First round lost to Alejandro Davidovich Fokina [Q]

The following players received wild cards into the main singles draw:

• Salvatore Caruso
• Gianluca Mager
• Lorenzo Musetti
• Stefano Travaglia

The following players received entry from the singles qualifying draw:

• Roberto Carballés Baena
• Alejandro Davidovich Fokina
• Federico Delbonis
• Hugo Dellien
• Kamil Majchrzak
• Cameron Norrie
• Tommy Paul

The following players received entry as lucky losers:

• Aljaž Bedene
• Yoshihito Nishioka

Before the tournament

• Borna Ćorić → replaced by Miomir Kecmanović
• Roger Federer → replaced by Reilly Opelka
• John Isner → replaced by Laslo Đere
• Guido Pella → replaced by Yoshihito Nishioka
• Casper Ruud → replaced by Aljaž Bedene
• Stan Wawrinka → replaced by Lloyd Harris

During the tournament

• Pablo Carreño Busta

• Hubert Hurkacz

• Main draw
• Qualifying draw