Angelique Kerber defeated Kateřina Siniaková in the final, 6–3, 6–2, to win the singles tennis title at the 2021 Bad Homburg Open. It was Kerber's 13th career WTA Tour singles title, her first in three years.[1][2]
This was the inaugural edition of the tournament.[3]
Bold denotes the mandatory tournaments (WTA 1000) † – Tournaments are affected by the COVID-19 pandemic * – Tournaments are introduced due to the impact of the COVID-19 pandemic