PROFILPELAJAR.COM

SIX5
Identifiers
Aliases	SIX5, BOR2, DMAHP, SIX homeobox 5
External IDs	OMIM: 600963; MGI: 106220; HomoloGene: 72248; GeneCards: SIX5; OMA:SIX5 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	45,769,252 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	18,832,474 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; right uterine tube; ; right ovary; ; myocardium of left ventricle; ; left ovary; ; parotid gland; ; canal of the cervix; ; right coronary artery; ; left uterine tube; ; body of uterus;
	Top expressed in
	ascending aorta; ; genital tubercle; ; aortic valve; ; corneal stroma; ; tail of embryo; ; cardiac muscle tissue of left ventricle; ; ventricular zone; ; molar; ; Gonadal ridge; ; male urethra;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription cis-regulatory region binding; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	nucleus; cytoplasm; transcription regulator complex;
Biological process	multicellular organism development; negative regulation of cell population proliferation; lens development in camera-type eye; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; spermatid development; negative regulation of skeletal muscle satellite cell proliferation; anatomical structure development;
	Sources:Amigo / QuickGO
Orthologs
	147912
	20475
	ENSG00000177045
	ENSMUSG00000040841
	Q8N196
	P70178
	NM_175875
	NM_011383
	NP_787071
	NP_035513
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein SIX5 is a protein that in humans is encoded by the SIX5 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000177045 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040841 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Boucher CA, King SK, Carey N, Krahe R, Winchester CL, Rahman S, Creavin T, Meghji P, Bailey ME, Chartier FL (Apr 1996). "A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeat". Hum Mol Genet. 4 (10): 1919–25. doi:10.1093/hmg/4.10.1919. PMID 8595416.
^ "Entrez Gene: SIX5 sine oculis homeobox homolog 5 (Drosophila)".