LBX1

LBX1
Identifiers
AliasesLBX1, HPX-6, HPX6, LBX1H, homeobox, ladybird homeobox 1, CCHS3
External IDsOMIM: 604255; MGI: 104867; HomoloGene: 4784; GeneCards: LBX1; OMA:LBX1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

10660

16814

Ensembl

ENSG00000138136

ENSMUSG00000025216

UniProt

P52954

P52955

RefSeq (mRNA)

NM_006562

NM_010691

RefSeq (protein)

NP_006553

NP_034821

Location (UCSC)Chr 10: 101.23 – 101.23 MbChr 19: 45.22 – 45.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transcription factor LBX1 is a protein that in humans is encoded by the LBX1 gene.[5][6]

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes.

In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138136 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025216 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jagla K, Dolle P, Mattei MG, Jagla T, Schuhbaur B, Dretzen G, Bellard F, Bellard M (Jul 1996). "Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes". Mech Dev. 53 (3): 345–56. doi:10.1016/0925-4773(95)00450-5. PMID 8645601. S2CID 19021832.
  6. ^ a b "Entrez Gene: LBX1 ladybird homeobox 1".

Further reading

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