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ATF7
Identifiers
Aliases	ATF7, ATFA, activating transcription factor 7
External IDs	OMIM: 606371; MGI: 2443472; HomoloGene: 4994; GeneCards: ATF7; OMA:ATF7 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	53,626,410 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,533,899 bp
RNA expression pattern
	Top expressed in
	popliteal artery; ; tibial arteries; ; gastric mucosa; ; epithelium of colon; ; Descending thoracic aorta; ; minor salivary glands; ; ascending aorta; ; right coronary artery; ; left coronary artery; ; sural nerve;
	Top expressed in
	neural layer of retina; ; muscle of thigh; ; yolk sac; ; lip; ; zygote; ; aortic valve; ; genital tubercle; ; ascending aorta; ; granulocyte; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; enzyme binding; DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; transcription factor binding; protein binding; metal ion binding; mitogen-activated protein kinase binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nuclear periphery; nucleus; nucleoplasm;
Biological process	viral process; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	11016
	223922
	ENSG00000170653
	ENSMUSG00000099083
	P17544
	Q8R0S1
NM_001130059; NM_001130060; NM_001206682; NM_001206683; NM_006856;
	NM_001366555; NM_001366556; NM_001366558; NM_001366561; NM_001366562; NM_001366563
	NM_146065; NM_001310066; NM_001310067; NM_001310070
NP_001123532; NP_001193611; NP_001193612; NP_006847; NP_001353484;
	NP_001353485; NP_001353487; NP_001353490; NP_001353491; NP_001353492
	NP_001296995; NP_001296996; NP_001296999
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclic AMP-dependent transcription factor ATF-7 is a protein that in humans is encoded by the ATF7 gene.^[5]^[6]^[7]

Homonym

In 2001, Peters et al. published a paper showing that ATF-7, a Novel bZIP Protein, interacts with PTP4A1.^[6] This ATF-7 is actually ATF5 and not ATF7, as noted by the authors at the end of their paper ("Note Added in Proof—While this manuscript was under review, sequences for mouse and human ATF-5 were deposited in GenBankTM. It appears that ATF-7 and ATF-5 are likely to be the same protein. In addition, an unrelated sequence named ATF7 has also been deposited in GenBankTM. In order to avoid confusion, future work on the protein described in this publication will likely refer to it as either ATF-5 or ATF-5/7.")^[6]