Fluclotizolam

Fluclotizolam Alerta sobre risco à saúde

Nome IUPAC	2-chloro-4-(2-fluorophenyl)-9-methyl-4H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepine
Identificadores
Número CAS	54123-15-8
PubChem	21317700
SMILES	`Fc4ccccc4C2=NCc1nnc(C)n1c3sc(Cl)cc23`
Propriedades
Fórmula química	C₁₅H₁₀ClFN₄S
Massa molar	332.78 g mol^-1
Farmacologia
Via(s) de administração	Oral
Página de dados suplementares
Estrutura e propriedades	n, ε_r, etc.
Dados termodinâmicos	Phase behaviour Solid, liquid, gas
Dados espectrais	UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a materiais sob condições normais de temperatura e pressão Referências e avisos gerais sobre esta caixa. Alerta sobre risco à saúde.

Fluclotizolam é um derivado da tienotriazolodiazepina que foi sintetizado pela primeira vez em 1979,^[1] mas nunca foi comercializado. Posteriormente, foi vendido como uma droga sintética, sendo identificado pela primeira vez definitivamente em 2017.^[2]^[3]^[4]

Ver também

Referências

↑ Hellerbach J, et al. Thienotriazolodiazepine derivatives. Patent US 4155913
↑ Zawilska JB, Wojcieszak J. An expanding world of New Psychoactive Substances – Designer benzodiazepines. NeuroToxicology 2019 July; 73: 8-16. doi:10.1016/j.neuro.2019.02.015
↑ Moosmann B., Auwärter V. (2018) Designer Benzodiazepines: Another Class of New Psychoactive Substances. In: Maurer H., Brandt S. (eds) New Psychoactive Substances. Handbook of Experimental Pharmacology, vol 252. doi:10.1007/164_2018_154
↑ Chetraru E, Ameline A, Gheddar L, Raul JS, Kintz P. Les designer benzodiazepines: qu’en sait-on aujourd’hui?. Toxicologie Analytique et Clinique. 2018 Feb 1;30(1):5-18. doi:10.1016/j.toxac.2017.12.001

Este artigo sobre fármacos é um esboço. Você pode ajudar a Wikipédia expandindo-o.

v d e Benzodiazepinas
1,4-benzodiazepínicos	2-oxoquazepam 3-hidroxifenazepam Bromazepam BMS-906024 Camazepam Carburazepam Clordiazepóxido Cinazepam Cinolazepam Clonazepam Cloniprazepam Clorazepato Ciprazepam Delorazepam Demoxepam Desmetilflunitrazepam Devazepida* Diazepam Diclazepam Difludiazepam Doxefazepam Elfazepam Carfluzepato de etilo Dirazepato de etila Loflazepato de etilo Flubromazepam Fletazepam Fludiazepam Flunitrazepam Flurazepam Flutemazepam Flutoprazepam Fosazepam Gidazepam Halazepam Iclazepam Irazepina Quenazepina Cetazolam Lorazepam Lormetazepam Lufuradom* Meclonazepam Medazepam Menitrazepam Metaclazepam Motrazepam Norflurazepam Nifoxipam Nimetazepam Nitemazepam Nitrazepam Nitrazepato Nordazepam Nortetrazepam Oxazepam Fenazepam Pinazepam Pivoxazepam Prazepam Proflazepam Quazepam QH-II-66 Reclazepam RO4491533* Ro05-4082 Ro5-4864* SH-I-048A Sulazepam Temazepam Tetrazepam Tifluadom* Timelotem* Tolufazepam Triflunordazepam Tuclazepam Uldazepam
1,5-benzodiazepínicos	Arfendazam Clobazam CP-1414S Lofendazam Triflubazam
2,3-benzodiazepínicos*	Girisopam GYKI-52466 GYKI-52895 Nerisopam Talampanel
Triazolobenzodiazepinas	Adinazolam Alprazolam Balovaptan* Bromazolam Clonazolam Estazolam Flualprazolam Flubromazolam Flunitrazolam Nitrazolam Fenazolam Pirazolam Rilmazolam (metabólito ativo de Rilmazafona) Triazolam
Imidazobenzodiazepinas	Bretazenil Climazolam EVT-201 FG-8205 Flumazenil GL-II-73 Imidazenil L-655.708 Loprazolam Midazolam PWZ-029 Remimazolam Ro15-4513 Ro48-6791 Ro48-8684 Ro4938581 Sarmazenil SH-053-R-CH3-2′F
Oxazolobenzodiazepinas	Cloxazolam Flutazolam Haloxazolam Mexazolam Oxazolam
Tienodiazepinas	Bentazepam Clotiazepam
Tienotriazolodiazepinas	Brotizolam Ciclotizolam Descloroetizolam Etizolam Fluclotizolam Israpafante* JQ1* Metizolam
Tienobenzodiazepinas*	Olanzapina Telenzapina
Piridodiazepinas	Lopirazepam
Piridotriazolodiazepinas	Zapizolam
Pirazolodiazepinas	Razobazam* Ripazepam Zolazepam Zomebazam Zometapina*
Pirrolodiazepinas	Premazepam
Tetrahidroisoquinobenzodiazepinas	Clazolam
Pirrolobenzodiazepinas*	Antramicina
Pró-fármacos benzodiazepínicos	Alprazolam triazolobenzofenona Avizafona Rilmazafona
* perfil de atividade atípica (não ligantes do receptor GABA_A)

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