Flubromazolam

Flubromazolam
Alerta sobre risco à saúde
Nome IUPAC 8-bromo-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a] [1,4]benzodiazepine
Identificadores
Número CAS 612526-40-6
PubChem 21930924
ChemSpider 10684757
SMILES
Propriedades
Fórmula química C17H12BrFN4
Massa molar 371.21 g mol-1
Farmacologia
Via(s) de administração Oral
Página de dados suplementares
Estrutura e propriedades n, εr, etc.
Dados termodinâmicos Phase behaviour
Solid, liquid, gas
Dados espectrais UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a
materiais sob condições normais de temperatura e pressão

Referências e avisos gerais sobre esta caixa.
Alerta sobre risco à saúde.

Flubromazolam é um triazolobenzodiazepínico, uma subclasse da classe dos benzodiazepínicos, em estágio de pesquisas científicas. Um átomo de flúor está ligado na posição R2' e um átomo de bromo na posição 7. É um dos benzodiazepínicos mais poderosos em termos de dose-efeito.

Os efeitos são considerados extremamente sedativos e hipnóticos, embora doses baixas proporcionem um efeito ansiolítico.[1]

É um fármaco extremamente poderoso, ativo a partir de um micrograma (0.001mg).[2]

Efeitos

O início dos efeitos após administração por via oral leva cerca de 30 minutos, e atinge o efeito máximo após 1 hora. Não é incomum que o usuário muitas vezes caia em sono profundo sem perceber, como consequência de seu rápido efeito.[2]

Mercado

O flubromazolam nunca foi comercializado, por ser um fármaco recente e devido à falta de estudos sobre o mesmo.

Referências

  1. «RCs - Flubromazolam». Bluelight.org (em inglês). Consultado em 11 de agosto de 2020 
  2. a b «Flubromazolam--A new life-threatening designer benzodiazepine». Clinical Toxicology (Philadelphia, Pa.). 54: 66–68. 2016. ISSN 1556-9519. PMID 26585557. doi:10.3109/15563650.2015.1112907 
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