Ro05-4082

Ro05-4082
Alerta sobre risco à saúde
Nome IUPAC 5-(2-chlorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
Identificadores
Número CAS
SMILES
Página de dados suplementares
Estrutura e propriedades n, εr, etc.
Dados termodinâmicos Phase behaviour
Solid, liquid, gas
Dados espectrais UV, IV, RMN, EM
Exceto onde denotado, os dados referem-se a
materiais sob condições normais de temperatura e pressão
Referências e avisos gerais sobre esta caixa.
Alerta sobre risco à saúde.

Ro05-4082 (N-metilclonazepam, ID-690) é um derivado de benzodiazepina desenvolvido na década de 1970. Ele tem propriedades sedativas e hipnóticas e tem quase a mesma potência do próprio clonazepam.[1] Mas nunca foi introduzido no uso clínico. É um isômero estrutural do meclonazepam (3-metilclonazepam) e, da mesma forma, foi vendido como um medicamento projetado, sendo identificado pela primeira vez na Suécia em 2017.[2][3]

Ver também

Referências

  1. ↑ Fukuda H, Kudo Y, Ono H, Togari A, Tanaka Y (janeiro 1977). «[Pharmacological study on 5-(o-chlorophenyl)-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (ID-690), with special reference to the effects on motor systems]». Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica (em japonês). 73 (1): 123–34. PMID 558942. doi:10.1254/fpj.73.123Acessível livremente 
  2. ↑ «Novel Benzodiazepines. A review of the evidence of use and harms of Novel Benzodiazepines.» (PDF). Advisory Council on the Misuse of Drugs. Abril 2020 
  3. ↑ «Methyl Clonazepam - PubChem Substance - NCBI». www.ncbi.nlm.nih.gov. Consultado em 9 de agosto de 2020 
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