PROFILPELAJAR.COM

SSBP2
Identifiers
Aliases	SSBP2, HSPC116, SOSS-B2, single stranded DNA binding protein 2
External IDs	OMIM: 607389; MGI: 1914220; HomoloGene: 22724; GeneCards: SSBP2; OMA:SSBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	81,751,797 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	91,703,429 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; popliteal artery; ; tibial arteries; ; gastric mucosa; ; Descending thoracic aorta; ; right coronary artery; ; canal of the cervix; ; left ovary;
	Top expressed in
	facial motor nucleus; ; olfactory epithelium; ; ciliary body; ; medial ganglionic eminence; ; thymus; ; epithelium of lens; ; vestibular sensory epithelium; ; Rostral migratory stream; ; vas deferens; ; barrel cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	single-stranded DNA binding; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding;
Cellular component	cytoplasm; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	23635
	66970
	ENSG00000145687
	ENSMUSG00000003992
	P81877
	Q9CYZ8
NM_001256732; NM_001256733; NM_001256734; NM_001256735; NM_001256736;
	NM_012446; NM_001345886; NM_001394350; NM_001394351; NM_001394352
	NM_024186; NM_024272; NM_001360775; NM_001360776
NP_001243661; NP_001243662; NP_001243663; NP_001243664; NP_001243665;
	NP_001332815; NP_036578
	NP_077148; NP_077234; NP_001347704; NP_001347705
	Wikidata
View/Edit Human	View/Edit Mouse

Single-stranded DNA-binding protein 2 is a protein that in humans is encoded by the SSBP2 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000145687 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003992 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
^ "Entrez Gene: SSBP2 single-stranded DNA binding protein 2".

Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Castro P, Liang H, Liang JC, Nagarajan L (2003). "A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity". Genomics. 80 (1): 78–85. doi:10.1006/geno.2002.6805. PMID 12079286.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Liang H, Samanta S, Nagarajan L (2005). "SSBP2, a candidate tumor suppressor gene, induces growth arrest and differentiation of myeloid leukemia cells". Oncogene. 24 (16): 2625–34. doi:10.1038/sj.onc.1208167. PMID 15782145.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Fleisig HB, Orazio NI, Liang H, et al. (2007). "Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes". Oncogene. 26 (33): 4797–805. doi:10.1038/sj.onc.1210281. PMID 17311003.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000145687 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003992 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11230166-5] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

[pmid11042152-6] Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.

[entrez-7] "Entrez Gene: SSBP2 single-stranded DNA binding protein 2".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

SSBP2

References

Further reading