RPL17

RPL17
Наявні структури
PDBПошук ортологів: PDBe RCSB
Ідентифікатори
Символи RPL17, L17, PD-1, RPL23, ribosomal protein L17
Зовнішні ІД OMIM: 603661 HomoloGene: 115574 GeneCards: RPL17
Ортологи
Види Людина Миша
Entrez
Ensembl
UniProt
RefSeq (мРНК)
NM_001181610
RefSeq (білок)
NP_012358
Локус (UCSC) Хр. 18: 49.49 – 49.49 Mb н/д
PubMed search [1] [2]
Вікідані
Див./Ред. для людейДив./Ред. для мишей

RPL17 (англ. Ribosomal protein L17) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 18-ї хромосоми.[3] Довжина поліпептидного ланцюга білка становить 184 амінокислот, а молекулярна маса — 21 397[4].

Послідовність амінокислот
1020304050
MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKD
VTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAES
NAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMIL
TEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE

Кодований геном білок за функціями належить до рибонуклеопротеїнів, рибосомних білків. Задіяний у такому біологічному процесі, як альтернативний сплайсинг.

Література

  • Mager D.L., Freeman J.D. (1990). A human gene related to the ribosomal protein L23 gene of Halobacterium marismortui. Nucleic Acids Res. 18: 5301—5301. PMID 2402465 doi:10.1093/nar/18.17.5301
  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14: 2121—2127. 2004. PMID 15489334 doi:10.1101/gr.2596504
  • Batra S.K., Metzgar R.S., Hollingsworth M.A. (1991). Isolation and characterization of a complementary DNA (PD-1) differentially expressed by human pancreatic ductal cell tumors. Cell Growth Differ. 2: 385—390. PMID 1793733

Примітки

  1. Human PubMed Reference:.
  2. Mouse PubMed Reference:.
  3. HUGO Gene Nomenclature Commitee, HGNC:10307 (англ.) . Процитовано 12 вересня 2017.{{cite web}}: Обслуговування CS1: Сторінки з параметром url-status, але без параметра archive-url (посилання)
  4. UniProt, P18621 (англ.) . Архів оригіналу за 7 серпня 2017. Процитовано 12 вересня 2017.

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