Рибосомні білки

Рибосомні білки — це білки, які разом із рибосомними РНК утворюють субодиниці рибосоми. Важливий внесок у дослідження білків рибосом зробила німецька дослідниця українського походження Марина Родніна.[1]

Консервативність

Рибосомні білки є одними з найбільш консервативними в живих організмів.[2]

З 40 білків малої субодиниці рибосоми, 15 є вкрай консервативними в прокаріот та евкаріот. 7 білків відомі лише в бактерій (S21, S6, S16, S18, S20, S21, and THX), а 17 білків наявні лише в археїв та евкаріот.[2]

18 білків великої субодиниці рибосоми є універсальними для всіх трьох доменів живого, 14 характерні для бактерій, 27 — для евкаріот та археїв.[2]

Див. також

Примітки

  1. ↑ Rodnina MV, Wintermeyer W (April 2011). The ribosome as a molecular machine: the mechanism of tRNA-mRNA movement in translocation. Biochemical Society Transactions. 39 (2): 658—62. doi:10.1042/BST0390658. PMID 21428957.
  2. ↑ а б в Ban N, Beckmann R, Cate JH, Dinman JD, Dragon F, Ellis SR, Lafontaine DL, Lindahl L, Liljas A, Lipton JM, McAlear MA, Moore PB, Noller HF, Ortega J, Panse VG, Ramakrishnan V, Spahn CM, Steitz TA, Tchorzewski M, Tollervey D, Warren AJ, Williamson JR, Wilson D, Yonath A, Yusupov M (February 2014). A new system for naming ribosomal proteins. Current Opinion in Structural Biology. 24: 165—9. doi:10.1016/j.sbi.2014.01.002. PMC 4358319. PMID 24524803.

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