Laksativ

Laksativi (purgativi, aperijenti) su hrana, hemijska jedinjenja, ili lekovi koji se uzimaju da bi se podstaklo pražnjenje creva ili omekšala stolica. Najčešće se koriste u lečenju konstipacije.[1] Pojedini stimulacioni, lubrikantni i soni laksativi se koriste za pražnjenje debelog creva radi rektalnog i/ili crevnog pregleda. U nekim slučajevima njihovo dejstvo se dopunjava primenom klistira.[2] Visoke doze laksativa uzrokuju dijareju. Laksativi deluju putem povećanja brzine kretanja fekalne materije duž debelog creva.

Neki laksativi kombinuju više aktivnih sastojaka, te proizvode kombinovana dejstva. Laksativi su dostupni u oralnoj ili supozitornoj formi.

Reference

  1. ↑ Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7. 
  2. ↑ Lamy PP, Krug BH (1978). „Review of laxative utilization in a skilled nursing facility”. Journal of the American Geriatrics Society 26 (12): 544-9. PMID 101574. 

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